Recommendations Summary
DM: Sucrose and Diabetes 2008
Click here to see the explanation of recommendation ratings (Strong, Fair, Weak, Consensus, Insufficient Evidence) and labels (Imperative or Conditional). To see more detail on the evidence from which the following recommendations were drawn, use the hyperlinks in the Supporting Evidence Section below.
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Recommendation(s)
DM: Sucrose Intake
If persons with diabetes choose to eat foods containing sucrose, the sucrose-containing foods should be substituted for other carbohydrate foods. Sucrose intakes of 10 to 35 percent of total energy intake do not have a negative effect on glycemic or lipid responses when substituted for isocaloric amounts of starch.
Rating: Strong
Conditional-
Risks/Harms of Implementing This Recommendation
- Excessive substitution of sucrose for starches could potentially contribute to inadequate intake of foods contributing other essential nutrients. If sucrose-containing foods are habitually added to usual intake, excessive energy intake is a concern.
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Conditions of Application
None.
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Potential Costs Associated with Application
- Although costs of MNT sessions and reimbursement vary, medical nutrition therapy sessions are essential for improved outcomes.
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Recommendation Narrative
- Sucrose intakes of 10 percent to 35 percent of total energy intake do not have a negative effect on glycemic or lipid responses in persons with either type 1 or type 2 diabetes when sucrose is substituted for isocaloric amounts of starch.
- Ten randomized crossover/controlled studies (Cooper et al, 1988, Loghmani et al, 1991, Nadeau et al, 2001, Peterson et al, 1986, Bantle, Laine et al, 1986, Bantle, Swanson et al, 1993, Buysschaert et al, 1987, Chantelau et al, 1985, Rickard et al, 2001, Santacroce et al, 1993), four non-randomized crossover studies (Malerbi et al, 1996, Coulston et al, 1985, Bantle, Laine et al, 1983, Schwingshandl et al, 1994), and one cross-over study (Shimakawa et al, 1993) examined the effect of sucrose on glycemic control. All but one study (Coulston et al, 1985) showed no effect of sucrose.
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Recommendation Strength Rationale
- Conclusion statement was given Grade I
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Minority Opinions
Consensus reached.
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Risks/Harms of Implementing This Recommendation
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Supporting Evidence
The recommendations were created from the evidence analysis on the following questions. To see detail of the evidence analysis, click the blue hyperlinks below (recommendations rated consensus will not have supporting evidence linked).
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References
Bantle JP, Laine DC, Castle GW, Thomas JW, Hoogwerf BJ, Goetz FC. Postprandial glucose and insulin responses to meals containing different carbohydrates in normal and diabetic subjects. New Eng J Med 1983; 309:7-12.
Bantle JP, Laine DC, Thomas JW. Metabolic effects of dietary fructose and sucrose in Types I and II diabetic subjects. JAMA 1986; 256:3241-3246.
Bantle JP, Swanson JE, Thomas W, Laine DC. Metabolic effects of dietary sucrose in type II diabetic subjects. Diabetes Care 1993; 16:1301-1305.
Buysschaert M, Sory R, Mpoy M, Lambert AE. Effect of the addition of simple sugars to mixed meals on the glycemic control of insulin treated diabetic patients. Diabete & Metabolisme 1987;13:625-629.
Chantelau EA, Gosseringer G, Sonnenberg GE, Berger M. Moderate intake of sucrose does not impair metabolic control in pump-treated diabetic outpatients. Diabetologia 1985; 29(4):204-207.
Cooper PL, Wahlqvist ML, Simpson RW. Sucrose versus saccharin as an added sweetener in non-insulin-dependent diabetes: short- and medium-term metabolic effects. Diabet Med. 1988 Oct; 5 (7): 676-680. PMID: 2975554.
Coulston AM, Hollenbeck CB, Donner CC, Williams R, Chiou YM, Reaven GM. Metabolic effects of added dietary sucrose in individuals with non-insulin-dependent diabetes mellitus (NIDDM). Metabolism 1985; 34(10):962-966.
Loghmani E, Rickard K, Washburne L, Vandagriff J, Fineberg N, Golden M. Glycemic response to sucrose-containing mixed meals in diets of children with insulin-dependent diabetes mellitus. Journal of Pediatrics 1991; 119:531-537.
Malerbi DA, Duarte AL, Paiva ESA, Wajchenberg BL. Metabolic effects of dietary sucrose and fructose in Type II diabetic subjects. Diabetes Care 1996:1249-1256.
Nadeau J, Koski KG, Strychar I, Yale JF. Teaching subjects with type 2 diabetes how to incorporate sugar choices into their daily meal plan promotes dietary compliance and does not deteriorate metabolic profile. Diabetes Care 2001; 24:222-227.
Peterson DB, Lambert J, Gerring S, Darling P, Carter RD, Jelfs R, Mann JI. Sucrose in the diet of diabetic patients - just another carbohydrate? Diabetologia 1986:29(4):216-220.
Rickard KA, Cleveland JL, Loghmani ES, Fineberg NS, Freidenberg GR. Similar glycemic responses to high versus moderate sucrose-containing foods in test meals for adolescents with type 1 diabetes and fasting euglycemia. J Am Diet Assoc 2001;101:1202-1205.
Santacroce G, Forlani G, Giangiulio S, Galuppi V, Pagani M, Vannini P. Long-term effects of eating sucrose on metabolic control of type 1 (insulin dependent) diabetic outpatients. Acta Diabetol Lat 1990; 27:365-370.
Schwingshandl J, Rippel S, Unterluggauer M, Borkenstein M. Effect of the introduction of dietary sucrose on metabolic control in children and adolescents with type 1 diabetes. Acta Diabetol 1994; 31:205-209.
Shimakawa T, Warram JH, Herrera-Acena MG, Krolewski AS. Usual dietary intake and hemoglobin A1 level in patients with insulin-dependent diabetes. J Am Diet Assoc 1993;93:1409-1412, 1415.
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References