• Intervention
    In adults, can sucralose be used to prevent and manage hyperlipidemias?
    • Conclusion

      One study of short duration and small sample size in men (Reyna et al, 2003), indicated that sucralose has no significant effect on lipid profile in adults. The evidence to determine whether sucralose can be used to prevent and manage hyperlipidemia is limited.

      The 2009 update did not find new studies meeting the inclusion criteria for this question; the Nutritive and Non-nutritive Sweeteners Workgroup (2009) reviewed and accepted the above study identified by the Non-nutritive Sweeteners Workgroup (2006).

    • Grade: III
      • Grade I means there is Good/Strong evidence supporting the statement;
      • Grade II is Fair;
      • Grade III is Limited/Weak;
      • Grade IV is Expert Opinion Only;
      • Grade V is Not Assignable.
      • High (A) means we are very confident that the true effect lies close to that of the estimate of the effect;
      • Moderate (B) means we are moderately confident in the effect estimate;
      • Low (C) means our confidence in the effect estimate is limited;
      • Very Low (D) means we have very little confidence in the effect estimate.
      • Ungraded means a grade is not assignable.
    In children, can sucralose be used to prevent and manage hyperlipidemias?
    • Conclusion

      To date, no studies were identified to evaluate the use of sucralose to prevent and manage hyperlipidemias in children.
       

       

    • Grade: V
      • Grade I means there is Good/Strong evidence supporting the statement;
      • Grade II is Fair;
      • Grade III is Limited/Weak;
      • Grade IV is Expert Opinion Only;
      • Grade V is Not Assignable.
      • High (A) means we are very confident that the true effect lies close to that of the estimate of the effect;
      • Moderate (B) means we are moderately confident in the effect estimate;
      • Low (C) means our confidence in the effect estimate is limited;
      • Very Low (D) means we have very little confidence in the effect estimate.
      • Ungraded means a grade is not assignable.