Better renal outcomes, as well as lower blood pressure and albuminuria levels have been shown in two RCTs and a small observational study among adults, non-dialyzed CKD patients on sodium restricted diets (alone or in combination with other behavioral intervention and protein restriction), compared with those who do not reduce sodium intakes. The prescribed sodium-restricted diets in the RCTs were targeted to sodium levels of 1,150mg to 1,840mg (MDRD study) and 1,955mg (a small RCT) per day. Weak observational data also support dietary protein and salt restriction to stabilize renal function in kidney transplant patients.

• Grade I means there is Good/Strong evidence supporting the statement;
• Grade II is Fair;
• Grade III is Limited/Weak;
• Grade IV is Expert Opinion Only;
• Grade V is Not Assignable.
• High (A) means we are very confident that the true effect lies close to that of the estimate of the effect;
• Moderate (B) means we are moderately confident in the effect estimate;
• Low (C) means our confidence in the effect estimate is limited;
• Very Low (D) means we have very little confidence in the effect estimate.
• Ungraded means a grade is not assignable.