• Assessment
    What is the individual magnitude of the response post-exposure to moderate cold compared to RMR at typical ambient temperature?
    • Conclusion

      Individual Errors

      In one high quality research design study of 10 women and 10 men (age range 19-36 y and BMI 17-32 kg/m2) residing in the Netherlands, the individual magnitude of the response three hours post-exposure to moderate cold
      (15° C or 59° F) compared to RMR at typical ambient temperature (22°C or 71.6° F) ranged from a decrease of 4% to an increase of 30% in winter and from a decrease of 12% to an increase of 24% in summer. RMR is affected, to variable degrees in given individuals, by moderate cold exposure or ambient room temperatures outside of a comfortable zone (22-25°C) for healthy adults.

    • Grade: V
      • Grade I means there is Good/Strong evidence supporting the statement;
      • Grade II is Fair;
      • Grade III is Limited/Weak;
      • Grade IV is Expert Opinion Only;
      • Grade V is Not Assignable.
      • High (A) means we are very confident that the true effect lies close to that of the estimate of the effect;
      • Moderate (B) means we are moderately confident in the effect estimate;
      • Low (C) means our confidence in the effect estimate is limited;
      • Very Low (D) means we have very little confidence in the effect estimate.
      • Ungraded means a grade is not assignable.
    Is control of temperature necessary to ensure an accurate RMR measure by indirect calorimetry in ill adult patients?
    • Conclusion

      Group mean Errors

      Two narrative reviews recommend measuring RMR in patients in a thermoneutral environment (no temperature range given).

       

    • Grade: IV
      • Grade I means there is Good/Strong evidence supporting the statement;
      • Grade II is Fair;
      • Grade III is Limited/Weak;
      • Grade IV is Expert Opinion Only;
      • Grade V is Not Assignable.
      • High (A) means we are very confident that the true effect lies close to that of the estimate of the effect;
      • Moderate (B) means we are moderately confident in the effect estimate;
      • Low (C) means our confidence in the effect estimate is limited;
      • Very Low (D) means we have very little confidence in the effect estimate.
      • Ungraded means a grade is not assignable.
    In burn patients, is control of temperature necessary to ensure an accurate RMR measure by indirect calorimetry?
    • Conclusion

      Group mean RMR measured at ambient room temperatures of 32° and 35° Celsius (89.6° and 95°F; closer to body temperature), were not related to burn size ranging from 20-97%. In contrast, group mean RMR was elevated when ambient temperatures were near thermoneutral conditions of 22-28°C, increased in proportion to burn size and greatest at 22°C (71.6°F).

    • Grade: II
      • Grade I means there is Good/Strong evidence supporting the statement;
      • Grade II is Fair;
      • Grade III is Limited/Weak;
      • Grade IV is Expert Opinion Only;
      • Grade V is Not Assignable.
      • High (A) means we are very confident that the true effect lies close to that of the estimate of the effect;
      • Moderate (B) means we are moderately confident in the effect estimate;
      • Low (C) means our confidence in the effect estimate is limited;
      • Very Low (D) means we have very little confidence in the effect estimate.
      • Ungraded means a grade is not assignable.
    What is the magnitude of the response on group mean RMR, post-exposure to moderate cold compared to typical ambient temperature?
    • Conclusion

      Group mean Errors

      In non US-residing healthy adults (age range 19-36 y ; BMI 17-32 kg/m2), after three-hours of moderate cold exposure (15° C or 59° F), the group mean RMR was increased 11.5±9.1% and 7.0±10.5% in winter and in summer seasons, respectively as compared to group mean RMR at comfortable ambient temperatures (22°C or 71.6° F). In a second international study of healthy adults (age range 20-29 and body fat % range of 9-21%), there were no significant group mean RMR differences in the summer season after sleeping in a room with ambient room temperatures of 20°C (68°F) or 25°C (77°F). In summary, group mean RMR is affected by variation from moderate cold exposure below a comfortable zone (22-25°C or 68-72 F) but not at comfortable temperatures.

       

    • Grade: III
      • Grade I means there is Good/Strong evidence supporting the statement;
      • Grade II is Fair;
      • Grade III is Limited/Weak;
      • Grade IV is Expert Opinion Only;
      • Grade V is Not Assignable.
      • High (A) means we are very confident that the true effect lies close to that of the estimate of the effect;
      • Moderate (B) means we are moderately confident in the effect estimate;
      • Low (C) means our confidence in the effect estimate is limited;
      • Very Low (D) means we have very little confidence in the effect estimate.
      • Ungraded means a grade is not assignable.