• Assessment
    Is there a relationship between hematopoietic cell transplant and its affect on mineral intake/absorption of cancer patients?
    • Conclusion
      One small, randomized group trial (positive quality) found that patients undergoing autologous bone marrow transplant experienced negative balance for copper, zinc and calcium. More studies of mineral deficiencies as a result of bone marrow transplant are needed.
    • Grade: III
      • Grade I means there is Good/Strong evidence supporting the statement;
      • Grade II is Fair;
      • Grade III is Limited/Weak;
      • Grade IV is Expert Opinion Only;
      • Grade V is Not Assignable.
      • High (A) means we are very confident that the true effect lies close to that of the estimate of the effect;
      • Moderate (B) means we are moderately confident in the effect estimate;
      • Low (C) means our confidence in the effect estimate is limited;
      • Very Low (D) means we have very little confidence in the effect estimate.
      • Ungraded means a grade is not assignable.
    • Search Plan and Results: HCT: Calories, Protein, Lipids, Nutritional Intake, EN/PN 2006
       
    Is there a relationship between hematopoietic cell transplant and its affect on the oral caloric intake of patients with hematologic malignancies?
    • Conclusion
      Three small studies (neutral-quality RCT, a positive-quality retrospective cohort and ) evaluated the oral intake of patients with hematologic malignancies undergoing BMT. Oral intake during BMT was less than required energy needs in all three studies. One study showed that the remission induction phase (versus consolidation and BMT phases) had a more prominent effect on the reduction of oral caloric intake. These studies observed that oral caloric intake was far below the required energy needs during the early post-transplant period.
    • Grade: III
      • Grade I means there is Good/Strong evidence supporting the statement;
      • Grade II is Fair;
      • Grade III is Limited/Weak;
      • Grade IV is Expert Opinion Only;
      • Grade V is Not Assignable.
      • High (A) means we are very confident that the true effect lies close to that of the estimate of the effect;
      • Moderate (B) means we are moderately confident in the effect estimate;
      • Low (C) means our confidence in the effect estimate is limited;
      • Very Low (D) means we have very little confidence in the effect estimate.
      • Ungraded means a grade is not assignable.
    • Search Plan and Results: HCT: Calories, Protein, Lipids, Nutritional Intake, EN/PN 2006