VN: Other Biomarkers of Disease (2023)

Intervention
In presumably healthy adults in the general population, what is the relationship between vegetarian diets and blood pressure?
- Conclusion
  In a recent systematic review of observational studies with presumably healthy adults in the general population, following a vegan diet may be associated with lower systolic, but not diastolic, blood pressure compared to non-vegetarian diets, but the evidence is uncertain (Very low certainty). Evidence was not available from recent systematic reviews to evaluate the impact of vegetarian diets that were not vegan on presumably healthy adults in the general population.
- Grade: Very Low (D)
  - Grade I means there is Good/Strong evidence supporting the statement;
  - Grade II is Fair;
  - Grade III is Limited/Weak;
  - Grade IV is Expert Opinion Only;
  - Grade V is Not Assignable.
  - High (A) means we are very confident that the true effect lies close to that of the estimate of the effect;
  - Moderate (B) means we are moderately confident in the effect estimate;
  - Low (C) means our confidence in the effect estimate is limited;
  - Very Low (D) means we have very little confidence in the effect estimate.
  - Ungraded means a grade is not assignable.
- Evidence Summary: In presumably healthy adults in the general population, what is the relationship between vegetarian diets and blood pressure?
- Search Plan and Results: VN: Vegetarian Nutrition and Disease Prevention (2023)
In presumably healthy adults in the general population, what is the relationship between vegetarian diets and LDL cholesterol?
- Conclusion
  In a recent systematic review of observational studies with presumably healthy adults in the general population, following a vegan diet may be associated with lower LDL-cholesterol concentrations compared to a non-vegetarian diet (Low certainty). Evidence was not available from recent systematic reviews to evaluate the impact of vegetarian diets that were not vegan on presumably healthy adults in the general population.
- Grade: Low (C)
  - Grade I means there is Good/Strong evidence supporting the statement;
  - Grade II is Fair;
  - Grade III is Limited/Weak;
  - Grade IV is Expert Opinion Only;
  - Grade V is Not Assignable.
  - High (A) means we are very confident that the true effect lies close to that of the estimate of the effect;
  - Moderate (B) means we are moderately confident in the effect estimate;
  - Low (C) means our confidence in the effect estimate is limited;
  - Very Low (D) means we have very little confidence in the effect estimate.
  - Ungraded means a grade is not assignable.
- Evidence Summary: In presumably healthy adults in the general population, what is the relationship between vegetarian diets and LDL cholesterol?
- Search Plan and Results: VN: Vegetarian Nutrition and Disease Prevention (2023)
In presumably healthy adults in the general population, what is the relationship between vegetarian diets and triglycerides?
- Conclusion
  In a recent systematic review of observational studies with presumably healthy adults in the general population, following a vegan diet may be associated with lower triglyceride concentrations compared to a non-vegetarian diet, but evidence is uncertain (Very Low certainty). Evidence was not available from recent systematic reviews to evaluate the impact of vegetarian diets that were not vegan on presumably healthy adults in the general population.
- Grade: Very Low (D)
  - Grade I means there is Good/Strong evidence supporting the statement;
  - Grade II is Fair;
  - Grade III is Limited/Weak;
  - Grade IV is Expert Opinion Only;
  - Grade V is Not Assignable.
  - High (A) means we are very confident that the true effect lies close to that of the estimate of the effect;
  - Moderate (B) means we are moderately confident in the effect estimate;
  - Low (C) means our confidence in the effect estimate is limited;
  - Very Low (D) means we have very little confidence in the effect estimate.
  - Ungraded means a grade is not assignable.
- Evidence Summary: In presumably healthy adults in the general population, what is the relationship between vegetarian diets and triglycerides?
- Search Plan and Results: VN: Vegetarian Nutrition and Disease Prevention (2023)
In presumably healthy adults in the general population, what is the relationship between vegetarian diets and C-reactive protein?
- Conclusion
  In recent systematic reviews of observational studies with presumably healthy adults in the general population, lacto-ovo vegetarian and vegan diets may be associated with lower C-reactive protein (CRP) concentrations compared to non-vegetarian diets, but evidence is uncertain.
- Grade: Very Low (D)
  - Grade I means there is Good/Strong evidence supporting the statement;
  - Grade II is Fair;
  - Grade III is Limited/Weak;
  - Grade IV is Expert Opinion Only;
  - Grade V is Not Assignable.
  - High (A) means we are very confident that the true effect lies close to that of the estimate of the effect;
  - Moderate (B) means we are moderately confident in the effect estimate;
  - Low (C) means our confidence in the effect estimate is limited;
  - Very Low (D) means we have very little confidence in the effect estimate.
  - Ungraded means a grade is not assignable.
- Evidence Summary: In presumably healthy adults in the general population, what is the relationship between vegetarian diets and C-reactive protein?
- Search Plan and Results: VN: Vegetarian Nutrition and Disease Prevention (2023)