Parker A, Byham Gray L, et al. 2014

25218597

The effect of medical nutrition therapy by a registered dietitian nutritionist in patients with prediabetes participating in a randomized controlled clinical research trial.

Parker A, Byham-Gray L, Denmark R, Winkle P

Journal of the Academy of Nutrition and Dietetics

2014

114

11

1739-1748

Randomized Controlled Trial

High risk

Inclusion criteria included male or female patients aged 18 years and older; no previous history or treatment for type 2 diabetes; IFG as defined as fasting plasma glucose >100 mg/dL (5.55 mmol/L) and 30 minutes a day, 5 days a week of moderate intensity physical activity).

A history of type 2 diabetes and/or use of antidiabetes medications; concomitant medication known to interfere with glucose metabolism, such as systemic corticosteroids; use of weight loss drugs; pregnancy or breastfeeding; refusal or inability to give informed consent to participate in the study; hospitalized for heart disease, stroke, or transient ischemic attack during the past 6 months; and mental incapacity, unwillingness, or language barrier precluding adequate understanding or cooperation.

Investigate the effect of medical nutrition therapy (MNT) compared with usual care on fasting plasma glucose values, glycated hemoglobin (HbA1c), serum lipid levels, and Diabetes Risk Score, from baseline to the end of a 12-week intervention in overweight or obese adults with prediabetes.

Not blinded

Anaheim, California, USA

Not-for-profit

This work was supported by a Diabetes Care and Education Dietetic Practice Group/Academy of Nutrition and Dietetics Foundation Diabetes MNT Outcomes Research award. Anaheim Clinical Trials sponsored the trial because subjects were seen at the research site.