• Assessment
    What is the role of nutritional status and nutrition care in the prevention of pressure ulcers in SCI? [SCI 2003)
    • Conclusion

      To prevent the development or reoccurrence of pressure ulcers, persons with spinal cord injury should have regular assessment of nutritional status with attention to risk factors associated with the development of pressure ulcers including weight status, adequacy of energy, protein, vitamin and mineral intake and laboratory values (prealbumin, total protein, albumin, hemoglobin, hematocrit, transferrin, and total lymphocyte count). Appropriate nutrition intervention should be initiated to achieve and maintain an optimal nutritional state.

    • Grade: II
      • Grade I means there is Good/Strong evidence supporting the statement;
      • Grade II is Fair;
      • Grade III is Limited/Weak;
      • Grade IV is Expert Opinion Only;
      • Grade V is Not Assignable.
      • High (A) means we are very confident that the true effect lies close to that of the estimate of the effect;
      • Moderate (B) means we are moderately confident in the effect estimate;
      • Low (C) means our confidence in the effect estimate is limited;
      • Very Low (D) means we have very little confidence in the effect estimate.
      • Ungraded means a grade is not assignable.
  • Intervention
    What is the evidence regarding dietary treatment of diarrhea/malabsorption in people with HIV infection?
    • Conclusion

      Seven studies were reviewed to evaluate dietary treatment of diarrhea/malabsorption in people with HIV infection. Many of these studies did not provide information on medications.  Two studies regarding fat malabsorption reported that consumption of medium chain triglycerides resulted in fewer stools, decreased stool fat and weight and increased fat absorption. Two studies regarding vitamin A and beta-carotene supplementation reported decreased gut permeability and risk of severe watery diarrhea. Further research regarding amino acid-based elemental diets, probiotics, pancreatic enzyme therapy, calcium carbonate, glutamine and the BRAT diet in people with HIV/AIDS is warranted, as well as the effect of medications.

       

    • Grade: II
      • Grade I means there is Good/Strong evidence supporting the statement;
      • Grade II is Fair;
      • Grade III is Limited/Weak;
      • Grade IV is Expert Opinion Only;
      • Grade V is Not Assignable.
      • High (A) means we are very confident that the true effect lies close to that of the estimate of the effect;
      • Moderate (B) means we are moderately confident in the effect estimate;
      • Low (C) means our confidence in the effect estimate is limited;
      • Very Low (D) means we have very little confidence in the effect estimate.
      • Ungraded means a grade is not assignable.
    What relationship do antioxidants, such as vitamins A, C and E and flavonoids, have on pathogenesis and/or exacerbations in patients with COPD?
    • Conclusion

      Eight studies regarding the relationship between antioxidants and COPD were reviewed.  Six studies report reduced serum and/or tissue levels of vitamins A, C and/or E in people with COPD.  Three studies regarding supplementation report insignificant effects, however these studies were limited in scope, duration and power.  Further research on the relationship between antioxidants and COPD is needed.   

    • Grade: III
      • Grade I means there is Good/Strong evidence supporting the statement;
      • Grade II is Fair;
      • Grade III is Limited/Weak;
      • Grade IV is Expert Opinion Only;
      • Grade V is Not Assignable.
      • High (A) means we are very confident that the true effect lies close to that of the estimate of the effect;
      • Moderate (B) means we are moderately confident in the effect estimate;
      • Low (C) means our confidence in the effect estimate is limited;
      • Very Low (D) means we have very little confidence in the effect estimate.
      • Ungraded means a grade is not assignable.
  • Monitoring and Evaluation
    (2005) Are there any unintended adverse effects when consuming stanols and sterols?
    • Conclusion

      It is unclear whether there are unintended adverse effects when consuming stanols and sterols. Some studies have observed no significant differences in plasma carotenoid concentrations, including alpha-carotene and lycopene and vitamins A, D and E, but other studies have found that alpha-tocopherol, alpha- and beta-carotene plasma concentrations decrease after consumption of sterols and stanols, even after adjusting for changes in plasma lipid levels.

    • Grade: V
      • Grade I means there is Good/Strong evidence supporting the statement;
      • Grade II is Fair;
      • Grade III is Limited/Weak;
      • Grade IV is Expert Opinion Only;
      • Grade V is Not Assignable.
      • High (A) means we are very confident that the true effect lies close to that of the estimate of the effect;
      • Moderate (B) means we are moderately confident in the effect estimate;
      • Low (C) means our confidence in the effect estimate is limited;
      • Very Low (D) means we have very little confidence in the effect estimate.
      • Ungraded means a grade is not assignable.