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Recommendations Summary

HTN: Soy Foods 2008

Click here to see the explanation of recommendation ratings (Strong, Fair, Weak, Consensus, Insufficient Evidence) and labels (Imperative or Conditional). To see more detail on the evidence from which the following recommendations were drawn, use the hyperlinks in the Supporting Evidence Section below.

  • Recommendation(s)

    Soy Foods

    Advise that the consumption of soy foods may or may not be beneficial for the reduction of blood pressure, since the effect of increased soy food intake on blood pressure is unclear.

    Rating: Weak

    • Risks/Harms of Implementing This Recommendation


    • Conditions of Application

      No conditions specified.

    • Potential Costs Associated with Application


    • Recommendation Narrative

      • In nine randomized trials, supplemented daily soy protein intake ranged from 18g to 40g per day or 70mg to 143mg per day of isoflavones for one month to one year; two of these studies included soy milk and yogurt.  While four of the nine trials reported no effect of soy or isoflavone intake on blood pressure (Jayagopal et al, 2002; Meyer et al, 2004; Hermansen et al, 2005; Kreijkamp-Kaspers et al, 2005) and one reported an increase in systolic blood pressure in women (Harrison et al, 2004), four trials reported that soy or isoflavone intake decreased systolic blood pressure by 4.3 to 18.4mm Hg and diastolic blood pressure by 2.8 to 15.9 mmHg (Teede et al, 2001; Rivas et al, 2002; Sagara et al, 2004; He et al, 2005). 
      • Cohort and cross-sectional studies reported conflicting findings between increased soy and isoflavone intake and reductions in blood pressure (Goodman-Gruen et al, 2001; Nagata et al, 2003; Yang et al, 2005).

    • Recommendation Strength Rationale

      • Conclusion Statement is Grade III

    • Minority Opinions

      Consensus reached.