Recommendations Summary

HTN: Food/Nutrient-Medication Interactions 2008

Click here to see the explanation of recommendation ratings (Strong, Fair, Weak, Consensus, Insufficient Evidence) and labels (Imperative or Conditional). To see more detail on the evidence from which the following recommendations were drawn, use the hyperlinks in the Supporting Evidence Section below.

• Recommendation(s)

  HTN: Food/Nutrient and Medication Interaction Assessment

  Dietitians should assess food/nutrient-medication interactions in patients that are on pharmacologic therapy for hypertension, as many antihypertensive medications interact with food and nutrients.

  Rating: Consensus
  Imperative

  • Risks/Harms of Implementing This Recommendation

    Adverse side effects and potential drug-nutrient interactions may be observed in some patients receiving pharmacologic therapy.

  • Conditions of Application

    Medications may be contraindicated or poorly tolerated in some individuals.

  • Potential Costs Associated with Application

    None.

  • Recommendation Narrative

    • Based on the JNC 7 report, although blood pressure control can be achieved in most patients who are hypertensive, many will require two or more antihypertensive medications.
    • Based on the JNC 7 report, failure to comply with lifestyle modifications and pharmacotherapy may result in inadequate blood pressure control.

  • Recommendation Strength Rationale

    The ADA Hypertension Expert Work Group concurs with the recommendations from the JNC 7, regarding food/nutrient and medication interactions.

    • Updated from The Sixth Report of the Joint National Committee on Prevention, Detection, Evaluation, and Treatment of High Blood Pressure.  Arch Intern Med 1997; 157:2413-46.
    • Published in The Seventh Report of the Joint National Committee on Prevention, Detection, Evaluation and Treatment of High Blood Pressure.  JAMA 2003;289:2560-71.

  • Minority Opinions

    Consensus reached.

• Supporting Evidence

  The recommendations were created from the evidence analysis on the following questions. To see detail of the evidence analysis, click the blue hyperlinks below (recommendations rated consensus will not have supporting evidence linked).

  • References
  • References not graded in Academy of Nutrition and Dietetics Evidence Analysis Process

    The Seventh Report of the Joint National Commitee on Prevention, Detection, Evaluation and Treatment of High Blood Pressure, NIH Publication No. 04-5230, August 2004, produced by the National Heart, Lung and Blood Institute in cooperation with the National High Blood Pressure Education Program.

    Available at:   

    http://www.nhlbi.nih.gov/guidelines/hypertension/

    To access the pdf of the JNC 7, click here: 

    http://www.nhlbi.nih.gov/guidelines/hypertension/jnc7full.htm