Recommendations Summary
Adult Weight Management (AWM) Determination of Resting Metabolic Rate
Click here to see the explanation of recommendation ratings (Strong, Fair, Weak, Consensus, Insufficient Evidence) and labels (Imperative or Conditional). To see more detail on the evidence from which the following recommendations were drawn, use the hyperlinks in the Supporting Evidence Section below.
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Recommendation(s)
AWM: Determining Energy Needs
Estimated energy needs should be based on RMR. If possible, RMR should be measured (e.g., indirect calorimetry). If RMR cannot be measured, then the Mifflin-St. Jeor equation using actual weight is the most accurate for estimating RMR for overweight and obese individuals.
Rating: Strong
ConditionalMifflin-St Jeor Equations
Men: RMR = (9.99 X weight) + (6.25 X height) – (4.92 X age) + 5
Women: RMR = (9.99 X weight )+ (6.25 X height) – (4.92 X age) – 161
Equations use weight in kilograms (kg), height in centimeters (cm).-
Risks/Harms of Implementing This Recommendation
The Mifflin-St. Jeor equation was not tested on racial groups other than Caucasian and so may not be accurate for these groups. Research separating obese from non-obese subjects is limited.
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Conditions of Application
Equations to estimate RMR should be used when RMR cannot be measured.
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Potential Costs Associated with Application
Costs vary by RMR measurement method.
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Recommendation Narrative
- Nine cross-sectional studies reported the evaluation of the Mifflin-St. Jeor equation in overweight and obese populations, however, only one separated obese from non-obese subjects. The Mifflin-St. Jeor equation predicted RMR within 10% of measured RMR in 70% of obese individuals; up to 9% were overestimations and up to 21% were underestimations (Arciero et al, 1993; De Lorenzo et al, 2001; Frankenfield et al, 2003; Garrel et al, 1996; Heshka et al, 1993; Liu et al, 1995; Mifflin et al, 1987; Scalfi et al, 1993; Taaffe et al, 1995)
- Eleven cross-sectional studies reported the evaluation of the Harris-Benedict equation in overweight and obese U.S. and Canadian populations, however, only five separated obese from non-obese subjects. In studies using actual weight, the Harris-Benedict equation predicted RMR within 10% of measured RMR in 39 - 64% of obese individuals; up to 43% were overestimations and up to 35% were underestimations. In studies using adjusted body weight, the Harris-Benedict equation predicted RMR within 10% of measured RMR in 0% - 60% of obese individuals; up to 25% were overestimations and up to 100% were underestimations (De Lorenzo et al, 2001; Feurer et al, 1983; Forman et al, 1998; Foster et al, 1988; Frankenfield et al, 2003; Heshka et al, 1993; Hirano et al, 2001; Mifflin et al, 1987; Owen et al, 1986; Owen et al, 1987; Pavlou et al, 1986).
- Ten cross-sectional studies reported the evaluation of the Owen equations in overweight and obese populations, however, only three separated obese from non-obese subjects. The Owen equations predicted RMR within 10% of measured RMR in 33 - 51% of individuals; up to 22% were overestimations and up to 60% were underestimations (Arciero et al, 1993; De Lorenzo et al, 2001; Frankenfield et al, 2003; Heshka et al, 1993; Mifflin et al, 1990; Owen et al, 1987; Owen et al, 1986; Scalfi et al, 1993; Siervo et al, 2003; Taaffe et al, 1995)
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Recommendation Strength Rationale
- Conclusion statements were Grade I and II
- Consistent findings across studies
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Minority Opinions
Consensus reached.
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Risks/Harms of Implementing This Recommendation
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Supporting Evidence
The recommendations were created from the evidence analysis on the following questions. To see detail of the evidence analysis, click the blue hyperlinks below (recommendations rated consensus will not have supporting evidence linked).
In obese adults, what is the prediction accuracy and maximum overestimation and understimation errors compared to measured resting metabolic rate when using the Harris-Benedict formula (actual body weight)?
In obese adults, what is the prediction accuracy and maximum overestimation and understimation errors compared to measured resting metabolic rate when using the Harris-Benedict formula (adjusted body weight)?
In obese adults, what is the prediction accuracy and maximum overestimation and understimation errors compared to measured resting metabolic rate when using the Harris-Benedict formula (ideal body weight)?
In obese adults, what is the prediction accuracy and maximum overestimation and underestimation resting metabolic rate (RMR) errors compared to measured RMR when using the WHO/FAO/UNU formula?
In obese adults, what is the prediction accuracy and maximum overestimation and understimation errors compared to measured resting metabolic rate when using the Owen et al formula?
In obese adults, what is the prediction accuracy and maximum overestimation and understimation errors compared to measured resting metabolic rate when using the Mifflin-St.Jeor formula?-
References
Arciero PJ, Goran MI, Gardner AW, Ades PA, Tyzbir RS, Poehlman ET. A practical equation to predict resting metabolic rate in older men. Metabolism. 1993; 42 (8): 950-957.
Case KO, Brahler CJ, Heiss C. Resting energy expenditures in Asian women measured by indirect calorimetry are lower than expenditures calculated from prediction equations. J Am Diet Assoc. 1997; 97(11): 1,288-1,292.
Clark HD, Hoffer LJ. Reappraisal of the resting metabolic rate of normal young men. Am J Clin Nutr. 1991; 53: 21-26.
Daly JM, Heymsfeld SB, Head A, Harvey LP, Nixon DW, Katzeff H, Grossman GD. Human energy requirements: overestimation by widely used prediction equation. Am J Clin Nutr 1985;42:1170-1174.
Feurer ID, Crosby LO Mullen JL. Measured and predicted resting energy expenditure in clinically stable patients. Clin Nutr. 1984;3:27-34.
Frankenfield DC, Muth ER, Rowe WA. The Harris-Benedict studies of human basal metabolism: History and limitations. J Am Diet Assoc. 1998;98:439-445.
Garrel DR, Jobin N, deJonge LHM. Should we still use the Harris and Benedict equations? Nutr Clin Prac 1996; 11: 99-103.
Roza AM, Shizgal HM. The Harris Benedict equation reevaluated: resting energy requirements and the body cell mass. Am J Clin Nutr. 1984;40:168-182.
Scalfi L, Coltorti A, Sapio C, DiBiase G, Borrelli R, Contaldo F. Predicted and measured resting energy expenditure in healthy young women. Clin Nutr. 1993; 12: 1-7.
Van der Ploeg GE, Withers RT. Predicting the resting metabolic rate of 30- 60-year-old Australian males. Eur J Clin Nutr 2002;56:701-708.
Vermeij CG, Feenstra BWA, Oomen MFA, deGraaf EJR, Zillikens MC, Swart GR, Bruining HA. Assessment of energy expenditure by indirect calorimetry in healthy subjects and patients with liver cirrhosis. J Parenter Enteral Nutr. 1991; 15: 421-425.
Censi L, Totai E, Pastore G, Ferro-Luzzi A. The basal metabolic rate and energy cost of standardized walking of short and tall men. Eur J Clin Nutr. 1998;52(6):441-446.
Ismail MN, Ng KK, Chee SS, Roslee R, Zawiah H. Predictive equations for the estimation of basal metabolic rate in Malaysian adults. Mal J Nutr. 1998;4:81-90.
Leung R, Woo J, Chan D, Tang N. Validation of prediction equations for basal metabolic rate in Chinese subjects. Eur J Clin Nutr. 2000;54(7):551-554.
Luhrman PM, Herbert BM, Krems C, Neuhauser-Berthold M. A new equation especially developed for predicting resting metabolic rate in the elderly for easy use in practice. Eur J Nutr. 2002;41(3):108-113.
Fredrix EWHM, Soeters PB, Deerenberg IM, Kester ADM, vonMeyenfeldt MF, Saris WHM, Resting and sleeping energy expenditure in the elderly. Eur J Clin Nutr. 1990; 44: 741-747.
Liu HY, Lu YF, Chen WJ. Predictive equations for basal metabolic rate in Chinese adults: A cross-validation study. J Am Diet Assoc. 1995; 95 (12): 1,403-1,408 and Liu HY, Lu YF, Chen WJ. Validity of predictive equations for the calculation of basal metabolic rate in healthy Chinese adults. Chinese Nutr Soc. 1994; 19 (2): 141-150.
Owen OE, Kavle E, Owen RS, Polansky M, Caprio S, Mozzoli MA, Kendrick ZV, Bushman MC, Boden G. A reappraisal of caloric requirements in healthy women. Am J Clin Nutr. 1986; 44: 1-19.
Arciero PJ, Goran MI, Gardner AM, Ades PA, Tyzbir RS, Poehlman ET. A practical equation to predict resting metabolic rate in older females. J Am Geriatr Soc. 1993; 41 (4): 389-395.
Siervo M, Boschi V, Falconi C. Which REE prediction equation should we use in normal-weight, overweight and obese women? Clin Nutr. 2003; 22(2): 193-204.
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References