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  • Assessment
    Do administration or changes in chemical use of alcohol have an acute effect on resting metabolic rate (RMR)?
    • Conclusion

      10/19/04

      Two small studies of moderate quality (one in healthy males and one in healthy females, ages 21 to 41 years) report individual RMR increases of 1.1 - 13.6% over 95 minutesa fter ingestion of alcohol in healthy men (Weststrate, Wunnick, et al, 1990) and mean RMR increases of 9.0% have been recorded 90-10 minutes post-ingestion in women (Klesges RC, Mealer CZ, et al, 1994).  In men, mean RMR increases of 4-6 % over 95 min or 124-287 kcal/24 hr, following 20-23 grams alcohol (140-251 kcals) consumption. These changes in RMR correspond with significant (P>0.05) decreases of 8-9% in respiratory quotient.  No data are available to indicate duration of the effect of alcohol on RMR

    • Grade: III
      • Grade I means there is Good/Strong evidence supporting the statement;
      • Grade II is Fair;
      • Grade III is Limited/Weak;
      • Grade IV is Expert Opinion Only;
      • Grade V is Not Assignable.
      • High (A) means we are very confident that the true effect lies close to that of the estimate of the effect;
      • Moderate (B) means we are moderately confident in the effect estimate;
      • Low (C) means our confidence in the effect estimate is limited;
      • Very Low (D) means we have very little confidence in the effect estimate.
      • Ungraded means a grade is not assignable.
    Do administration or changes in chemical use of alcohol have a chronic effect on resting metabolic rate (RMR)?
    • Conclusion

      10/19/04

      In one study of neutral quality rating, middle-aged alcoholics (mean age 42 y), the RMR was elevated (26%) due to chronic alcohol intake but decreased to levels similar to that of non-alcoholic controls within 14 days of abstention.  

    • Grade: III
      • Grade I means there is Good/Strong evidence supporting the statement;
      • Grade II is Fair;
      • Grade III is Limited/Weak;
      • Grade IV is Expert Opinion Only;
      • Grade V is Not Assignable.
      • High (A) means we are very confident that the true effect lies close to that of the estimate of the effect;
      • Moderate (B) means we are moderately confident in the effect estimate;
      • Low (C) means our confidence in the effect estimate is limited;
      • Very Low (D) means we have very little confidence in the effect estimate.
      • Ungraded means a grade is not assignable.
    Do administration or changes in chemical use of alcohol have an effect on resting metabolic rate (RMR) when alcohol is consumed with food?
    • Conclusion

      10/19/04

      No effect is consistently supported in diet-induced thermogenesis when alcohol is administered with food. 

    • Grade: II
      • Grade I means there is Good/Strong evidence supporting the statement;
      • Grade II is Fair;
      • Grade III is Limited/Weak;
      • Grade IV is Expert Opinion Only;
      • Grade V is Not Assignable.
      • High (A) means we are very confident that the true effect lies close to that of the estimate of the effect;
      • Moderate (B) means we are moderately confident in the effect estimate;
      • Low (C) means our confidence in the effect estimate is limited;
      • Very Low (D) means we have very little confidence in the effect estimate.
      • Ungraded means a grade is not assignable.