While there are recognizable benefits of the use of nonnutritive sweeteners with the maintenance of blood glucose control, to date[2008] there is limited evidence to support the use or nonuse of nonnutritive sweetners (NNS) in pregnancy, and even less evidence addressing this issue specifically in gestational diabetes mellitus (GDM).   The FDA has approved aspartame, acesulfame potassium, sucralose, saccharin and neotame for general use, while stevia has not been approved.  The use of FDA-approved nonnutritive sweeteners during pregnancy is acceptable with the exception of aspartame for pregnant women with hyperphenylalanine in the blood and phenylketonuria.  The American Medical Association suggests avoiding saccharin during pregnancy due to possible slow fetal clearance.