18 publications were reviewed to evaluate physical activity for people with HIV infection. Two recent systematic Cochrane reviews conclude that performing constant or interval aerobic exercise, progressive resistance exercise, or a combination of both, for at least 20 minutes per session at a frequency of three times per week is generally safe in adults with HIV infection and may lead to significant improvements in strength, endurance, cardiopulmonary fitness and reductions in depressive symptoms. Studies published since that time support those findings, however, research on the relationship between physical activity and immunity in people with HIV is inconclusive. Special considerations may be needed for people with HIV infection who have reduced aerobic capacity, metabolic changes, increased pain, fatigue and impairments while exercising and those with a history of drug and alcohol abuse. Further research is needed on the effect of physical activity on serum lipid profile in people with HIV infection.
