Seven studies were evaluated regarding medical nutrition therapy (MNT) and/or nutrition counseling in people with HIV infection. One study, completed prior to highly active antiretroviral therapy, stressed that early intervention may prevent progressive weight loss. Four studies regarding MNT reported improved outcomes related to energy intake and/or symptoms (with or without oral nutritional supplementation) and cardiovascular risk indices, especially with increased frequency of visits. Two studies regarding nutritional counseling (non-MNT) also reported improved outcomes related to weight gain, CD4 count and quality of life

• Grade I means there is Good/Strong evidence supporting the statement;
• Grade II is Fair;
• Grade III is Limited/Weak;
• Grade IV is Expert Opinion Only;
• Grade V is Not Assignable.
• High (A) means we are very confident that the true effect lies close to that of the estimate of the effect;
• Moderate (B) means we are moderately confident in the effect estimate;
• Low (C) means our confidence in the effect estimate is limited;
• Very Low (D) means we have very little confidence in the effect estimate.
• Ungraded means a grade is not assignable.