Several studies have reported that people with celiac disease are more likely to experience neurological symptoms such as depression, cerebellar ataxia, headaches and migraines, and neuropathy than healthy controls. Early diagnosis and compliance with a gluten-free dietary pattern may reduce the prevalence of symptoms related to cerebellar ataxia, headaches and migraines. Six studies report that compliance with a gluten-free dietary pattern has not been shown to have an effect on depressive symptoms; one study suggests that this may relate more to family history of depression. Evidence is less conclusive and/or limited regarding the effect of a gluten-free dietary pattern on epilepsy, anxiety, regional cerebral perfusion, hypotonia, learning disorders and disruptive behavior disorders; additional research is needed in these areas.