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Intervention
For the patient with heart failure,does supplementing with thiamine provide beneficial outcomes?
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Conclusion
Two small randomized controlled trials suggest that patients with heart failure may improve thiamine status with high-dose supplementation. However, only one study reported a benefit in clinical symptoms (LVEF increased and mean NYHA class decreased).
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Grade: III
- Grade I means there is Good/Strong evidence supporting the statement;
- Grade II is Fair;
- Grade III is Limited/Weak;
- Grade IV is Expert Opinion Only;
- Grade V is Not Assignable.
- High (A) means we are very confident that the true effect lies close to that of the estimate of the effect;
- Moderate (B) means we are moderately confident in the effect estimate;
- Low (C) means our confidence in the effect estimate is limited;
- Very Low (D) means we have very little confidence in the effect estimate.
- Ungraded means a grade is not assignable.
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Conclusion