PDM: Metabolic Syndrome (2013)

PDM: Metabolic Syndrome (2013)

• Assessment
  In adults with metabolic syndrome, what is the impact of whole or refined grains, independent of weight loss, on glycemic-related outcomes (such as fasting blood glucose, random blood glucose, two-hour post-prandial blood glucose, A1C)?

  • Conclusion

    Limited research reports no significant impact of whole or refined grains, independent of weight loss, on fasting blood glucose or two-hour post-prandial blood glucose levels in adults with metabolic syndrome.

    Additional longer-term intervention studies are needed to ascertain an effect of whole or refined grains on glycemic-related outcomes in adults with metabolic syndrome with or without meeting the metabolic syndrome criteria for impaired glucose tolerance and impaired fasting glucose.

  • Grade: III
    • Grade I means there is Good/Strong evidence supporting the statement;
    • Grade II is Fair;
    • Grade III is Limited/Weak;
    • Grade IV is Expert Opinion Only;
    • Grade V is Not Assignable.
    • High (A) means we are very confident that the true effect lies close to that of the estimate of the effect;
    • Moderate (B) means we are moderately confident in the effect estimate;
    • Low (C) means our confidence in the effect estimate is limited;
    • Very Low (D) means we have very little confidence in the effect estimate.
    • Ungraded means a grade is not assignable.
  • Evidence Summary: In adults with metabolic syndrome, what is the impact of whole or refined grains, independent of weight loss, on glycemic-related outcomes (such as fasting blood glucose, random blood glucose, two-hour post-prandial blood glucose, A1C)?
    • Detail
    • Quality Rating Summary
      For a summary of the Quality Rating results, click here.
    • Worksheets
      • Katcher HI, Legro RS, Kunselman AR, Gillies PJ, Demers LM, Bagshaw DM, Kris-Etherton PM. The effects of a whole grain-enriched hypocaloric diet on cardiovascular disease risk factors in men and women with metabolic syndrome. Am J Clin Nutr. 2008; 87: 79-90.
  • Search Plan and Results: PDM: Whole and Refined Grains and Metabolic Syndrome 2012
     
  In adults with metabolic syndrome, what is the impact of whole or refined grains, independent of weight loss, on lipid outcomes (TG, HDL)?

  • Conclusion

    Limited research reports no significant impact of whole or refined grains, independent of weight loss, on triglyceride or HDL cholesterol levels in adults with metabolic syndrome.

    Additional longer-term intervention studies are needed to ascertain an effect of whole or refined grains on lipid outcomes in adults with metabolic syndrome with or without meeting the metabolic syndrome criteria for lipid levels.

  • Grade: III
    • Grade I means there is Good/Strong evidence supporting the statement;
    • Grade II is Fair;
    • Grade III is Limited/Weak;
    • Grade IV is Expert Opinion Only;
    • Grade V is Not Assignable.
    • High (A) means we are very confident that the true effect lies close to that of the estimate of the effect;
    • Moderate (B) means we are moderately confident in the effect estimate;
    • Low (C) means our confidence in the effect estimate is limited;
    • Very Low (D) means we have very little confidence in the effect estimate.
    • Ungraded means a grade is not assignable.
  • Evidence Summary: In adults with metabolic syndrome, what is the impact of whole or refined grains, independent of weight loss, on lipid outcomes (TG, HDL)?
    • Detail
    • Quality Rating Summary
      For a summary of the Quality Rating results, click here.
    • Worksheets
      • Katcher HI, Legro RS, Kunselman AR, Gillies PJ, Demers LM, Bagshaw DM, Kris-Etherton PM. The effects of a whole grain-enriched hypocaloric diet on cardiovascular disease risk factors in men and women with metabolic syndrome. Am J Clin Nutr. 2008; 87: 79-90.
  • Search Plan and Results: PDM: Whole and Refined Grains and Metabolic Syndrome 2012
     
  In adults with metabolic syndrome, what is the impact of whole or refined grains, independent of weight loss, on anthropometric outcomes (WC, WHR)?

  • Conclusion

    Limited research reports no significant impact of whole or refined grains, independent of weight loss, on waist circumference in adults with metabolic syndrome.

    Additional longer-term intervention studies are needed to ascertain an effect of whole or refined grains on anthropometric outcomes in adults with metabolic syndrome with or without meeting the metabolic syndrome criteria for anthropometric measures.

  • Grade: III
    • Grade I means there is Good/Strong evidence supporting the statement;
    • Grade II is Fair;
    • Grade III is Limited/Weak;
    • Grade IV is Expert Opinion Only;
    • Grade V is Not Assignable.
    • High (A) means we are very confident that the true effect lies close to that of the estimate of the effect;
    • Moderate (B) means we are moderately confident in the effect estimate;
    • Low (C) means our confidence in the effect estimate is limited;
    • Very Low (D) means we have very little confidence in the effect estimate.
    • Ungraded means a grade is not assignable.
  • Evidence Summary: In adults with metabolic syndrome, what is the impact of whole or refined grains, independent of weight loss, on anthropometric outcomes (WC, WHR)?
    • Detail
    • Quality Rating Summary
      For a summary of the Quality Rating results, click here.
    • Worksheets
      • Katcher HI, Legro RS, Kunselman AR, Gillies PJ, Demers LM, Bagshaw DM, Kris-Etherton PM. The effects of a whole grain-enriched hypocaloric diet on cardiovascular disease risk factors in men and women with metabolic syndrome. Am J Clin Nutr. 2008; 87: 79-90.
  • Search Plan and Results: PDM: Whole and Refined Grains and Metabolic Syndrome 2012
     
  In adults with metabolic syndrome, what is the impact of whole or refined grains, independent of weight loss, on blood pressure?

  • Conclusion

    Limited research reports no significant impact of whole or refined grains, independent of weight loss, on systolic or diastolic blood pressure in adults with metabolic syndrome.

    Additional longer-term intervention studies are needed to ascertain the effect of whole or refined grains on blood pressure in adults with metabolic syndrome with or without meeting the metabolic syndrome criteria for blood pressure.

  • Grade: III
    • Grade I means there is Good/Strong evidence supporting the statement;
    • Grade II is Fair;
    • Grade III is Limited/Weak;
    • Grade IV is Expert Opinion Only;
    • Grade V is Not Assignable.
    • High (A) means we are very confident that the true effect lies close to that of the estimate of the effect;
    • Moderate (B) means we are moderately confident in the effect estimate;
    • Low (C) means our confidence in the effect estimate is limited;
    • Very Low (D) means we have very little confidence in the effect estimate.
    • Ungraded means a grade is not assignable.
  • Evidence Summary: In adults with metabolic syndrome, what is the impact of whole or refined grains, independent of weight loss, on blood pressure?
    • Detail
    • Quality Rating Summary
      For a summary of the Quality Rating results, click here.
    • Worksheets
      • Katcher HI, Legro RS, Kunselman AR, Gillies PJ, Demers LM, Bagshaw DM, Kris-Etherton PM. The effects of a whole grain-enriched hypocaloric diet on cardiovascular disease risk factors in men and women with metabolic syndrome. Am J Clin Nutr. 2008; 87: 79-90.
  • Search Plan and Results: PDM: Whole and Refined Grains and Metabolic Syndrome 2012
     
• Intervention
  In adults with metabolic syndrome, what is the impact of whole or refined grains, independent of weight loss, on renal outcomes?

  • Conclusion

    There were no studies identified to evaluate the impact of whole or refined grains, independent of weight loss, on renal outcomes in adults with metabolic syndrome.

    Intervention studies are needed to ascertain an effect of whole or refined grains on renal outcomes in adults with metabolic syndrome with or without meeting the metabolic syndrome criteria for renal measures.

  • Grade: V
    • Grade I means there is Good/Strong evidence supporting the statement;
    • Grade II is Fair;
    • Grade III is Limited/Weak;
    • Grade IV is Expert Opinion Only;
    • Grade V is Not Assignable.
    • High (A) means we are very confident that the true effect lies close to that of the estimate of the effect;
    • Moderate (B) means we are moderately confident in the effect estimate;
    • Low (C) means our confidence in the effect estimate is limited;
    • Very Low (D) means we have very little confidence in the effect estimate.
    • Ungraded means a grade is not assignable.
  • Search Plan and Results: PDM: Whole and Refined Grains and Metabolic Syndrome 2012