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  • Intervention
    In outpatient adults, what is the effectiveness of MNT provided by a Registered Dietitian Nutritionist (RDN) to improve disorders of lipid metabolism outcomes?
    • Conclusion
      Strong evidence supports the effectiveness of multiple visits (two to 12 visits; 60-minute initial visit and 20- to 45-minute follow-ups) for Medical Nutrition Therapy (MNT) by a nutrition professional (registered dietitian nutritionist or equivalent) in adults with disorders of lipid metabolism. Evidence showed improved total cholesterol (-2.3mg to -47.9mg per dL), LDL-cholesterol (-6.0mg to -21.7mg per dL), triglycerides (-12mg to -175mg/dL), HLD-cholesterol (+2.0mg to +4.0mg per dL), weight (-4.3kg to -12.6kg), waist circumference (-0.6cm to -9.3cm) and BMI (-0.2kg/m2 to -2.6kg/m2). MNT may also result in reductions in need for lipid-lowering medications.
    • Grade: I
      • Grade I means there is Good/Strong evidence supporting the statement;
      • Grade II is Fair;
      • Grade III is Limited/Weak;
      • Grade IV is Expert Opinion Only;
      • Grade V is Not Assignable.
      • High (A) means we are very confident that the true effect lies close to that of the estimate of the effect;
      • Moderate (B) means we are moderately confident in the effect estimate;
      • Low (C) means our confidence in the effect estimate is limited;
      • Very Low (D) means we have very little confidence in the effect estimate.
      • Ungraded means a grade is not assignable.
    In outpatient adults, what is the cost benefit of MNT provided by a Registered Dietitian Nutritionist (RDN) to improve disorders of lipid metabolism outcomes?
    • Conclusion

      Consistent evidence supports the cost-effectiveness, cost benefit and economic savings of outpatient Medical Nutrition Therapy (MNT) provided by a nutrition professional (registered dietitian nutritionist or equivalent) in patients with disorders of lipid metabolism (three or more MNT visits over six weeks to three months). Using a variety of cost-effectiveness analyses, the studies affirm that MNT resulted in improved clinical outcomes (total cholesterol and LDL-cholesterol, -6% to -13%; triglycerides, -11% to -22%; HDL-cholesterol, ­+4%; BMI, -4%; quality adjusted life years, +0.75 years to 0.78 years) and lower medication use (savings of $638 to $1,456 per year) in patients with disorders of lipid metabolism. Increased time spent with a nutrition professional resulted in greater improvements. Continued research is needed on the cost-effectiveness, cost benefit and economic savings of outpatient MNT for disorders of lipid metabolism.

    • Grade: I
      • Grade I means there is Good/Strong evidence supporting the statement;
      • Grade II is Fair;
      • Grade III is Limited/Weak;
      • Grade IV is Expert Opinion Only;
      • Grade V is Not Assignable.
      • High (A) means we are very confident that the true effect lies close to that of the estimate of the effect;
      • Moderate (B) means we are moderately confident in the effect estimate;
      • Low (C) means our confidence in the effect estimate is limited;
      • Very Low (D) means we have very little confidence in the effect estimate.
      • Ungraded means a grade is not assignable.