Sodium

NA: Other Sodium Compounds (2010)

• Assessment
  Is there a relationship between sodium bicarbonate intake and blood pressure in normotensive adults?

  • Conclusion

    One positive-quality RCT showed that there is no relationship between sodium bicarbonate (NaHCO₃) intake and blood pressure in normotensive adults. More research in this area is needed.

  • Grade: III
    • Grade I means there is Good/Strong evidence supporting the statement;
    • Grade II is Fair;
    • Grade III is Limited/Weak;
    • Grade IV is Expert Opinion Only;
    • Grade V is Not Assignable.
    • High (A) means we are very confident that the true effect lies close to that of the estimate of the effect;
    • Moderate (B) means we are moderately confident in the effect estimate;
    • Low (C) means our confidence in the effect estimate is limited;
    • Very Low (D) means we have very little confidence in the effect estimate.
    • Ungraded means a grade is not assignable.
  • Evidence Summary: Sodium Bicarbonate Intake and Blood Pressure in Normotensive Adults
    • Detail
    • Quality Rating Summary
      For a summary of the Quality Rating results, click here.
    • Worksheets
      • Luft FC, Zemel MB, Sowers JA, Fineberg NS, Weinberger MH. Sodium bicarbonate and sodium chloride: Effects on blood pressure and electrolyte homeostasis in normal and hypertensive man. J Hypertens. 1990 Jul; 8(7): 663-70. PMID: 2168457
  • Search Plan and Results: NA: Sodium Bicarbonate, Citrate, Glutamate and Blood Pressure - 2009
     
  Is there a relationship between sodium citrate intake and blood pressure in normotensive adults?

  • Conclusion

    There is no evidence to suggest a relationship between sodium citrate intake and blood pressure in normotensive adults. More research is needed in this area.

  • Grade: V
    • Grade I means there is Good/Strong evidence supporting the statement;
    • Grade II is Fair;
    • Grade III is Limited/Weak;
    • Grade IV is Expert Opinion Only;
    • Grade V is Not Assignable.
    • High (A) means we are very confident that the true effect lies close to that of the estimate of the effect;
    • Moderate (B) means we are moderately confident in the effect estimate;
    • Low (C) means our confidence in the effect estimate is limited;
    • Very Low (D) means we have very little confidence in the effect estimate.
    • Ungraded means a grade is not assignable.
  • Search Plan and Results: NA: Sodium Bicarbonate, Citrate, Glutamate and Blood Pressure - 2009
     
  Is there a relationship between sodium glutamate intake and blood pressure in normotensive adults?

  • Conclusion

    There is no evidence to suggest a relationship between sodium glutamate intake and blood pressure in normotensive adults. More research is needed in this area.

  • Grade: V
    • Grade I means there is Good/Strong evidence supporting the statement;
    • Grade II is Fair;
    • Grade III is Limited/Weak;
    • Grade IV is Expert Opinion Only;
    • Grade V is Not Assignable.
    • High (A) means we are very confident that the true effect lies close to that of the estimate of the effect;
    • Moderate (B) means we are moderately confident in the effect estimate;
    • Low (C) means our confidence in the effect estimate is limited;
    • Very Low (D) means we have very little confidence in the effect estimate.
    • Ungraded means a grade is not assignable.
  • Search Plan and Results: NA: Sodium Bicarbonate, Citrate, Glutamate and Blood Pressure - 2009