Nutritive and Non-Nutritive Sweeteners

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NNNS: Saccharin (2010-2011)

The Saccharin topic contains the following sub-topics and questions: 

Effect of Saccharin on Appetite/Food Intake

  • In adults, does saccharin affect food intake in adults?
  • In adults, does using foods or beverages with saccharin affect appetite?
  • In children, does saccharin affect food intake?
  • In children, does using foods or beverages with saccharin affect appetite?

Effect of Saccharin on Energy Balance

  • In adults, does using foods or beverages with saccharin in a calorie-restricted or ad libitum diet affect energy balance?
  • In children, does using beverages with saccharin in a calorie-restricted or ad libitum diet affect energy balance (weight)?

Energy Density and Saccharin

  • Do intakes of saccharin affect energy density?

Estimated and Acceptable Intake of Saccharin

  • What is the estimated saccharin consumption level and is it within acceptable daily intake (ADI) limits?

Nutrient Quality and Saccharin

  • Do intakes of saccharin and the foods and beverages to which it is added, assist adult consumers in meeting recommended dietary goals?
  • Do intakes of saccharin and the foods and beverages to which it is added, assist child consumers in meeting recommended dietary goals?

Health Risks and Acceptable Intake of Saccharin

Diabetes, Glycemic Response and Saccharin

  • In adults, can saccharin be used to manage diabetes and glycemic response?
  • In children, can saccharin be used to manage diabetes and glycemic response?
  • In adults with diabetes, what is the intake of saccharin and is this within the Acceptable Daily Intake (ADI) of non-nutritive sweeteners?
  • In children with diabetes, what is the intake of saccharin, and is this within the Acceptable Daily Intake (ADI) of non-nutritive sweeteners?

Behavior Changes, Cognitive Function, Moods and Saccharin

  • Does saccharin affect behavior changes, cognitive function or moods?

Hyperlipidemias and Saccharin

  • In adults, can saccharin be used to prevent and manage hyperlipidemias?
  • In children, can saccharin be used to prevent and manage hyperlipidemias?

Adverse Effects of Saccharin

  • What is the evidence from human subjects research that saccharin consumption is associated with adverse effects in the general population?