Nutritive and Non-Nutritive Sweeteners

NNNS: Sucralose (2010-2011)

The Sucralose topic contains the following sub-topics and questions: 

Effect of Sucralose and Energy Balance

  • In adults, does using foods or beverages with sucralose in a calorie-restricted or ad libitum diet affect energy balance?
  • In children, does using beverages with sucralose in a calorie-restricted or ad libitum diet affect energy balance (weight)?

Effect of Sucralose on Appetite/Food Intake

  • In adults, does sucralose affect food intake?
  • In children, does sucralose affect food intake?
  • In adults, does using foods or beverages with sucralose affect appetite?
  • In children, does using foods or beverages with sucralose affect appetite?

Nutrient Quality and Sucralose

  • Do intakes of sucralose, and the foods and beverages to which it is added, assist consumers in meeting recommended dietary goals?

Energy Density and Sucralose

  • Do intakes of sucralose affect energy density?

Estimated and Acceptable Intake of Sucralose

  • What is the estimated sucralose consumption level and is it within acceptable daily intake (ADI) limits?

Health Risks and Benefits of Sucralose

Diabetes, Glycemic Response and Sucralose

  • In adults, can sucralose be used to manage diabetes and glycemic response?
  • Can sucralose be used to manage diabetes and glycemic response?
  • In children, can sucralose be used to manage diabetes and glycemic response?
  • What is the intake of sucralose in persons with diabetes and is this within the Acceptable Daily Intake (ADI) of non-nutritive sweeteners?

Behavior Changes, Cognitive Function, Moods and Sucralose

  • Does sucralose affect behavior changes, cognitive function or moods?

Hyperlipidemias and Sucralose

  • In adults, can sucralose be used to prevent and manage hyperlipidemias?
  • In adults, can sucralose be used to prevent and manage hyperlipidemias?
  • In children, can sucralose be used to prevent and manage hyperlipidemias?

Adverse Effects of Sucralose

  • What is the evidence from human subjects research that sucralose consumption is associated with adverse effects in the general population?
  • What is the evidence from human subjects research that sucralose consumption is associated with adverse effects in the general population?

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