Nutritive and Non-Nutritive Sweeteners

NNNS: Effect Appetite/Food Intake (2011)

• Intervention
  In adults, does saccharin affect food intake in adults?

  • Conclusion

    Saccharin does not increase food intake in adults. Modest energy savings can result if saccharin-sweetened foods replace sugar-sweetened products in a form that is also lower in energy.

    The 2009 update did not find new studies meeting the inclusion criteria for this question; the Nutritive and Non-nutritive Sweeteners Workgroup (2009) reviewed and accepted the studies identified by the Non-nutritive Sweeteners Workgroup (2006).

  • Grade: III
    • Grade I means there is Good/Strong evidence supporting the statement;
    • Grade II is Fair;
    • Grade III is Limited/Weak;
    • Grade IV is Expert Opinion Only;
    • Grade V is Not Assignable.
    • High (A) means we are very confident that the true effect lies close to that of the estimate of the effect;
    • Moderate (B) means we are moderately confident in the effect estimate;
    • Low (C) means our confidence in the effect estimate is limited;
    • Very Low (D) means we have very little confidence in the effect estimate.
    • Ungraded means a grade is not assignable.
  • Evidence Summary: In adults, does saccharin affect food intake?
    • Detail
    • Quality Rating Summary
      For a summary of the Quality Rating results, click here.
    • Worksheets
      • Canty DJ, Chan MM. Effects of consumption of caloric vs. non caloric sweet drinks on indices of hunger and food consumption in normal adults. Am J Clin Nutr. 1991; 53: 1159-64.
      • Renwick AG. Intense Sweeteners, Food Intake, and the weight of a body of Evidence. Physiology and Behavior, 1994, vol. 55, p. 139-143.
      • Rogers PJ, Blundell JE. Separating the actions of sweetness and calories: Effects of saccharin and carbohydrates on humger and food intake in human subjects. Physiology and Behavior, 1989, vol. 45, p. 1,093-1,099.
  • Search Plan and Results: Saccharin 2009
     
  In adults, does using foods or beverages with saccharin affect appetite?

  • Conclusion

    In short-term studies, saccharin does not affect appetite in adults. 

    The 2009 update did not find new studies meeting the inclusion criteria for this question; the Nutritive and Non-nutritive Sweeteners Workgroup (2009) reviewed and accepted the studies identified by the Non-nutritive Sweeteners Workgroup (2006).

     

  • Grade: III
    • Grade I means there is Good/Strong evidence supporting the statement;
    • Grade II is Fair;
    • Grade III is Limited/Weak;
    • Grade IV is Expert Opinion Only;
    • Grade V is Not Assignable.
    • High (A) means we are very confident that the true effect lies close to that of the estimate of the effect;
    • Moderate (B) means we are moderately confident in the effect estimate;
    • Low (C) means our confidence in the effect estimate is limited;
    • Very Low (D) means we have very little confidence in the effect estimate.
    • Ungraded means a grade is not assignable.
  • Evidence Summary: In adults, does saccharin affect appetite?
    • Detail
    • Quality Rating Summary
      For a summary of the Quality Rating results, click here.
    • Worksheets
      • Canty DJ, Chan MM. Effects of consumption of caloric vs. non caloric sweet drinks on indices of hunger and food consumption in normal adults. Am J Clin Nutr. 1991; 53: 1159-64.
      • Renwick AG. Intense Sweeteners, Food Intake, and the weight of a body of Evidence. Physiology and Behavior, 1994, vol. 55, p. 139-143.
      • Rogers PJ, Blundell JE. Separating the actions of sweetness and calories: Effects of saccharin and carbohydrates on humger and food intake in human subjects. Physiology and Behavior, 1989, vol. 45, p. 1,093-1,099.
  • Search Plan and Results: Saccharin 2009
     
  In children, does saccharin affect food intake?

  • Conclusion

    To date, no studies were identified to evaluate the effect of saccharin on food intake in children.

    
    

     

  • Grade: V
    • Grade I means there is Good/Strong evidence supporting the statement;
    • Grade II is Fair;
    • Grade III is Limited/Weak;
    • Grade IV is Expert Opinion Only;
    • Grade V is Not Assignable.
    • High (A) means we are very confident that the true effect lies close to that of the estimate of the effect;
    • Moderate (B) means we are moderately confident in the effect estimate;
    • Low (C) means our confidence in the effect estimate is limited;
    • Very Low (D) means we have very little confidence in the effect estimate.
    • Ungraded means a grade is not assignable.
  • Search Plan and Results: Saccharin 2009
     
  In children, does using foods or beverages with saccharin affect appetite?

  • Conclusion

    To date, no studies were identified to evaluate the effect of saccharin on appetite in children.

  • Grade: V
    • Grade I means there is Good/Strong evidence supporting the statement;
    • Grade II is Fair;
    • Grade III is Limited/Weak;
    • Grade IV is Expert Opinion Only;
    • Grade V is Not Assignable.
    • High (A) means we are very confident that the true effect lies close to that of the estimate of the effect;
    • Moderate (B) means we are moderately confident in the effect estimate;
    • Low (C) means our confidence in the effect estimate is limited;
    • Very Low (D) means we have very little confidence in the effect estimate.
    • Ungraded means a grade is not assignable.
  • Search Plan and Results: Saccharin 2009