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Basic Research
Vitamin E (Hyperlipidemia 2001)
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Conclusion
Vitamin E intake has been associated with decreased risk for cardiovascular death and nonfatal MI in observational studies (cohort and cross-sectional) and nonfatal MI in one RCT (CHAOS) in subjects with CAD. However, three other RCT using 400 IU/d of vitamin E supplementaion for 4 to 5 years had no impact on the incidence of non-fatal or fatal CHD.
This information is from the 2001 Hyperlipidemia project.
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Grade: II
- Grade I means there is Good/Strong evidence supporting the statement;
- Grade II is Fair;
- Grade III is Limited/Weak;
- Grade IV is Expert Opinion Only;
- Grade V is Not Assignable.
- High (A) means we are very confident that the true effect lies close to that of the estimate of the effect;
- Moderate (B) means we are moderately confident in the effect estimate;
- Low (C) means our confidence in the effect estimate is limited;
- Very Low (D) means we have very little confidence in the effect estimate.
- Ungraded means a grade is not assignable.
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Conclusion