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  • Assessment
    In studies of non-obese or non-obese and obese adults, what are the group mean errors in estimating resting metabolic rate when using the Mifflin-St. Jeor formula?
    • Conclusion

      A study of neutral quality research design reported group RMR mean overestimation errors in primarily obese, U.S. residing females (mean BMI 38.5±11.4 but including 23 non-obese individuals with a BMI of 24-28 kg/m2), the Mifflin-St. Jeor equation underestimated group mean by 23 kcals/day. Two high quality research design study in non-obese Italian women (~18-30 y) reported a group mean overestimation error of ~65-90 kcals/day. A high quality research design study of Italian non-obese men and women (age range of 18-59 years) found a group RMR mean underestimation error of 86-96 kcals/day. In this same study, with all weights represented, the group mean underestimation error difference was ~100 kcals/day.

    • Grade: I
      • Grade I means there is Good/Strong evidence supporting the statement;
      • Grade II is Fair;
      • Grade III is Limited/Weak;
      • Grade IV is Expert Opinion Only;
      • Grade V is Not Assignable.
      • High (A) means we are very confident that the true effect lies close to that of the estimate of the effect;
      • Moderate (B) means we are moderately confident in the effect estimate;
      • Low (C) means our confidence in the effect estimate is limited;
      • Very Low (D) means we have very little confidence in the effect estimate.
      • Ungraded means a grade is not assignable.
    In studies of obese adults, what is the group mean error in estimating resting metabolic rate (RMR) compared to measured RMR when using the Mifflin-St. Jeor formula?
    • Conclusion

      A study of neutral quality research design reported group RMR mean overestimation error of 132 kcal/d in obese, U.S. residing males. In obese Italian men and women (ages 18-59 years), the Mifflin-St. Jeor equation underestimated group mean RMR by 145 and 120 kcals/d, respectively. In obese Italian women, the Mifflin-St. Jeor equation overestimated group mean of 10 kcals/day with a 95% confidence interval of an overestimation by 298 kcals/d and an underestimation of 279 kcals/day.

    • Grade: I
      • Grade I means there is Good/Strong evidence supporting the statement;
      • Grade II is Fair;
      • Grade III is Limited/Weak;
      • Grade IV is Expert Opinion Only;
      • Grade V is Not Assignable.
      • High (A) means we are very confident that the true effect lies close to that of the estimate of the effect;
      • Moderate (B) means we are moderately confident in the effect estimate;
      • Low (C) means our confidence in the effect estimate is limited;
      • Very Low (D) means we have very little confidence in the effect estimate.
      • Ungraded means a grade is not assignable.