Folate supplementation (0.8-5.0mg daily), given with other micronutrient supplements, may result in beneficial outcomes in patients with heart failure. Possible benefits include: Decrease in homocysteine levels, endothelium-dependent vasodilator acetylcholine and arterial blood pressure and improvements in left ventricular volume, ejection fraction and quality of life scores.
Vitamin B12 supplementation (200mcg to 500mcg daily), given with other micronutrient supplements, may result in beneficial outcomes in patients with heart failure. Possible benefits include: Decreases in homocysteine levels, endothelium-dependent vasodilator acetylcholine, arterial blood pressure and improvements in left ventricular volume, ejection fraction and quality of life scores.