CKD: Protein Energy Supplements: Dialysate (2018)

Intervention
What is the effect of nutritional supplementation via dialysate on anthropometric measurements in adults with CKD on peritoneal dialysis?
- Conclusion
  In peritoneal dialysis (PD) patients displaying signs of protein-energy malnutrition, substituting 1-2 daily exchanges of dextrose dialysate for 1.1% AA dialysate had no effect on anthropometric outcomes, but results were limited (two studies).
- Grade: III
  - Grade I means there is Good/Strong evidence supporting the statement;
  - Grade II is Fair;
  - Grade III is Limited/Weak;
  - Grade IV is Expert Opinion Only;
  - Grade V is Not Assignable.
  - High (A) means we are very confident that the true effect lies close to that of the estimate of the effect;
  - Moderate (B) means we are moderately confident in the effect estimate;
  - Low (C) means our confidence in the effect estimate is limited;
  - Very Low (D) means we have very little confidence in the effect estimate.
  - Ungraded means a grade is not assignable.
- Evidence Summary: What is the effect of nutritional supplementation via dialysate on anthropometric measurements in adults with CKD on peritoneal dialysis?
- Search Plan and Results: CKD: Macronutrients : Nutritional Supplements (2018)
What is the effect of nutritional supplementation via dialysate on electrolyte levels in adults with CKD on peritoneal dialysis?
- Conclusion
  In patients on peritoneal dialysis (PD) displaying signs of protein-energy malnutrition, substituting 1-2 daily exchanges of dextrose dialysate for 1.1% AA dialysate decreased participant phosphate (two studies) and bicarbonate (one study) levels, but results regarding effect on participant potassium levels was unclear (two studies).
- Grade: III
  - Grade I means there is Good/Strong evidence supporting the statement;
  - Grade II is Fair;
  - Grade III is Limited/Weak;
  - Grade IV is Expert Opinion Only;
  - Grade V is Not Assignable.
  - High (A) means we are very confident that the true effect lies close to that of the estimate of the effect;
  - Moderate (B) means we are moderately confident in the effect estimate;
  - Low (C) means our confidence in the effect estimate is limited;
  - Very Low (D) means we have very little confidence in the effect estimate.
  - Ungraded means a grade is not assignable.
- Evidence Summary: What is the effect of nutritional supplementation via dialysate on electrolyte levels in adults with CKD on peritoneal dialysis?
- Search Plan and Results: CKD: Macronutrients : Nutritional Supplements (2018)
What is the effect of nutritional supplementation via dialysate on lipid profile in adults with CKD on peritoneal dialysis?
- Conclusion
  In peritoneal dialysis (PD) patients displaying signs of protein-energy malnutrition, substituting one daily exchange of dextrose dialysate for 1.1% AA dialysate had no effect on LDL or HDL (one study) or total cholesterol or triglyceride levels (two studies).
- Grade: III
  - Grade I means there is Good/Strong evidence supporting the statement;
  - Grade II is Fair;
  - Grade III is Limited/Weak;
  - Grade IV is Expert Opinion Only;
  - Grade V is Not Assignable.
  - High (A) means we are very confident that the true effect lies close to that of the estimate of the effect;
  - Moderate (B) means we are moderately confident in the effect estimate;
  - Low (C) means our confidence in the effect estimate is limited;
  - Very Low (D) means we have very little confidence in the effect estimate.
  - Ungraded means a grade is not assignable.
- Evidence Summary: What is the effect of nutritional supplementation via dialysate on lipid profile in adults with CKD on peritoneal dialysis?
- Search Plan and Results: CKD: Macronutrients : Nutritional Supplements (2018)
What is the effect of nutritional supplementation via dialysate on nutritional status indicators in adults with CKD on peritoneal dialysis?
- Conclusion
  In peritoneal dialysis (PD) patients displaying signs of protein-energy malnutrition, substituting 1-2 daily exchanges of dextrose dialysate for 1.1% AA dialysate did not affect albumin, pre-albumin, transferrin or total protein levels compared to those receiving dextrose dialysate only.
- Grade: III
  - Grade I means there is Good/Strong evidence supporting the statement;
  - Grade II is Fair;
  - Grade III is Limited/Weak;
  - Grade IV is Expert Opinion Only;
  - Grade V is Not Assignable.
  - High (A) means we are very confident that the true effect lies close to that of the estimate of the effect;
  - Moderate (B) means we are moderately confident in the effect estimate;
  - Low (C) means our confidence in the effect estimate is limited;
  - Very Low (D) means we have very little confidence in the effect estimate.
  - Ungraded means a grade is not assignable.
- Evidence Summary: What is the effect of nutritional supplementation via dialysate on nutritional status indicators in adults with CKD on peritoneal dialysis?
- Search Plan and Results: CKD: Macronutrients : Nutritional Supplements (2018)