Nutritional Genomics

NG: Adverse Events (2018-19)

• Intervention
  In adults, what adverse events are reported from interventions incorporating results of genetic testing into nutrition counselling and care?

  • Conclusion

    In healthy adults, there were no adverse events reported as a result of participation in one RCT in which results of genetic testing were incorporated into nutrition counselling and care as compared to counselling or care that did not incorporate genetic results.

  • Grade: III
    • Grade I means there is Good/Strong evidence supporting the statement;
    • Grade II is Fair;
    • Grade III is Limited/Weak;
    • Grade IV is Expert Opinion Only;
    • Grade V is Not Assignable.
    • High (A) means we are very confident that the true effect lies close to that of the estimate of the effect;
    • Moderate (B) means we are moderately confident in the effect estimate;
    • Low (C) means our confidence in the effect estimate is limited;
    • Very Low (D) means we have very little confidence in the effect estimate.
    • Ungraded means a grade is not assignable.
  • Evidence Summary: In children and adults, what adverse events are reported from interventions incorporating results of genetic testing into nutrition counselling and care?
    • Detail
    • Quality Rating Summary
      For a summary of the Quality Rating results, click here.
    • Worksheets
      • Celis-Morales C, Livingstone K, Marsaux C, Macready A, Fallaize R, O'Donovan C, Woolhead C, Forster H, Walsh M, Navas-Carretero S, San-Cristobal R, Tsirigoti L, Lambrinou C, Mavrogianni C, Moschonis G, Kolossa S, Hallmann J, Godlewska M, Surwillo A, Traczyk I, Drevon C, Bouwman J, van Ommen B, Grimaldi K, Parnell L, Matthews J, Manios Y, Daniel H, Martinez J, Lovegrove J, Gibney E, Brennan L, Saris W, Gibney M, Mathers J. Effect of personalized nutrition on health-related behaviour change: evidence from the Food4Me European randomized controlled trial. International Journal of Epidemiology 2017; 46:578-588
  • Search Plan and Results: NG: Incorporating Results of Genetic Testing into Nutrition Counseling or Care (2019)
     
  In children, what adverse events are reported from interventions incorporating results of genetic testing into nutrition counselling and care?

  • Conclusion

    No included articles reported adverse events from incorporating results of genetic testing in nutrition counseling and care in children.

  • Grade: V
    • Grade I means there is Good/Strong evidence supporting the statement;
    • Grade II is Fair;
    • Grade III is Limited/Weak;
    • Grade IV is Expert Opinion Only;
    • Grade V is Not Assignable.
    • High (A) means we are very confident that the true effect lies close to that of the estimate of the effect;
    • Moderate (B) means we are moderately confident in the effect estimate;
    • Low (C) means our confidence in the effect estimate is limited;
    • Very Low (D) means we have very little confidence in the effect estimate.
    • Ungraded means a grade is not assignable.