NPA-GP: Behavioral Outcomes (2021)
Author and Year:
Rosas L, Xiao L, et al, 2021
PubMed ID:
Article Title:
Understanding mechanisms of integrated behavioral therapy for co-occurring obesity and depression in primary care: a mediation analysis in the RAINBOW trial.
Authors:
Rosas L, Xiao L, Lv N,Lavori P, Venditti E, Snowden M, Smyth J, Lewis M, Williams L, Suppes T, Goldstein-Piekarski A, Ma J
Journal:
Translational Behavioral Medicine
Year of publication:
2021
Volume:
11
Issue:
2
Page numbers:
382-392
Study Design:
Randomized Controlled Trial
Risk of Bias Assessment Rating:
Low risk
Inclusion Criteria:
Adults of any sex and race/ethnicity were eligible if they (1) had a body mass index (BMI; calculated as weight in kilograms divided by height in meters squared) of 30 or greater (27 for Asian adults), (2) had depressive symptoms defined by a 9-item Patient Health Questionnaire (PHQ-9) score of 10 or greater,16,17 and (3) did not have any serious comorbidities or meet any other exclusion criteria (eg, pregnancy, inability to speak or read English, and plan to relocate).
Exclusion Criteria:
Those with significant medical (e.g., type 2 diabetes mellitus or cardiovascular disease) or psychiatric
comorbidities (e.g., psychotic or bipolar disorders) or special lifestyle circumstances
Research Purpose:
To test the hypothesis that an integrated collaborative care intervention would significantly improve both obesity and depression at 12 months compared with usual care.
Blinding efforts:
Study Location:
Source(s) of Funding:
Government, University/Hospital
Please specify names of funders:
This research was supported by award R01HL119453 from the National Heart, Lung, and Blood Institute and internal funding from the Palo Alto Medical Foundation Research Institute and the University of Illinois, Chicago.
Trial Name if applicable:
RAINBOW