Silver T, Papadopoulou A, et al. 2018

28891084

Structured advice provided by a dietitian increases adherence of consumers to diet and lifestyle changes and lowers blood low-density lipoprotein (LDL)-cholesterol: the increasing adherence of consumers to diet & lifestyle changes to lower (LDL) cholesterol (ACT) randomised controlled trial.

Sialvera T, Papadopoulou A, Efstathiou S, Trautwein E, Ras R, Kollia N, Farajian P, Goumas G, Dimakopoulos I, Papavasiliou K, Koutsouri A, Zampelas A

Journal of Human Nutrition and Dietetics

2018

31

2

197-208

Randomized Controlled Trial

Low risk

Key inclusion criteria were defined as men and women >45 years and <70 years, TC between 200 –250 mg dL-1 (5.18–6.47 mmol L–1), triglycerides (TG) <300 mg dL-1 (3.39 mmol L-1) and systolic blood pressure ,160 mmHg.

Exclusion criteria were having a body mass index (BMI) 30 kg m-2, familial hypercholesterolaemia, history of phytosterolaemia, severe concomitant diseases, coronary event and food allergies, and, for women, being pregnant, trying to become pregnant or breast-feeding. Individuals were also excluded if they had previously consumed or were currently consuming foods or supplements containing PS or plant stanols, were using cholesterol-lowering medication or anti-diabetic drugs, were already included in other epidemiological studies and/or clinical trials, were smoking,

The present study aimed to investigate the effect of structured dietary advice provided by a dietitian compared to standard advice provided by a physician on dietary changes including the consumption of foods with added plant sterols on lowering serum cholesterol levels during a 6-week intervention programme. In addition, the study assessed whether these dietary behavioural modifications were maintained during another 6-week follow-up period under real-life conditions.

None disclosed

Athens, Greece

University/Hospital

The study was supported by an unrestricted grant from Unilever R&D.