CRDA: Inflammatory Marker Outcomes (2023)

Author and Year:
Davis C, Bryan J, et al. 2017
PubMed ID:
Article Title:
A Mediterranean Diet Reduces F-Isoprostanes and Triglycerides among Older Australian Men and Women after 6 Months.
Davis C, Bryan J, Hodgson J, Woodman R, Murphy K
Journal of Nutrition
Year of publication:
Page numbers:
Study Design:
Randomized Controlled Trial
Risk of Bias Assessment Rating:
Some concerns
Inclusion Criteria:
>/- 65 years; non-smokers; free of chronic disease (e.g. cancer, gastrointestinal disease, renal, hepatic disease etc.); free of major psychological conditions (e.g. diagnosed dementia or severe depression).
Exclusion Criteria:
Considered by the investigator to be unwilling, unlikely or unable to comprehend or comply with the study protocol; current smoker; uncontrolled HTN (>170/100); vegetarian (does not eat red meat, poultry or fish); actively undertaking a weight loss program; use of appetite suppressants or Orlistat (Xenical) BMI >135 kg; age <65 years; previous/current traumatic head/brain injury, neurological or psychiatric conditions; previous stroke; unstable use of anti-depressant medication (<6 months); current or recent (in the last 6 months) malignancy; major liver, kidney, respiratory or gastrointestinal disease; current cardiovascular disease or angina; age and education; adjusted DemTect scores <13
Research Purpose:
To determine whether adherence to a MedDiet would result in changes to plasma lipids, glucose and insulin, high-sensitivity C-reactive protein (hs-CRP) and F2-7 isprostanes (F2-IsoP)
Blinding efforts:
Study Location:
Source(s) of Funding:
Government, Government, Industry
Please specify names of funders:
National Health and Medical Research Council, Cobram Estate provided Australian extra-virgin olive oil, Peanut Company of Australia provided hi-oleic dry roast peanuts, Grains & Legumes Nutrition Council sourced legumes, Simplot Australia Pty. Ltd. provided canned legumes and tuna; Goodman Fielder Ltd. provided canola oil; and the Almond Board of Australia provided almonds.