HTN: Medical Nutrition Therapy (2022-24)
Author and Year:
                            
                                Agewall S, Wikstrand J, Samuelsson O, et al. 1994 
                            
                        
                
                            PubMed ID:
                            
                        
                
                            Article Title:
                            
                                The efficacy of multiple risk factor intervention in treated hypertensive men during long-term follow up. Risk Factor Intervention Study Group. 
                            
                        
                
                            Authors:
                            
                                Agewall S, Wikstrand J, Samuelsson O, Persson B, Andersson O, Fagerberg B 
                            
                        
                
                            Journal:
                            
                                Journal of internal medicine 
                            
                        
                
                            Year of publication:
                            
                                1994 
                            
                        
                
                            Volume:
                            
                                236 
                            
                        
                
                            Issue:
                            
                                6 
                            
                        
                
                            Page numbers:
                            
                                651-659 
                            
                        
                
                            Study Design:
                            
                                Randomized Controlled Trial 
                            
                        
                
                            Risk of Bias Assessment Rating:
                             Some concerns
 
                                    Some concerns 
                            Inclusion Criteria:
                            
                                Apart from treatment of hypertension, the inclusion criteria were male sex, aged 50-72 years, and one or more of the following: serum cholesterol > 6.5 mmol L-1 (mean of two values measured before inclusion in the study, during the preceding year); tobacco smoking >/= 1 cigarette per day); or diabetes mellitus. 
                            
                        
                
                            Exclusion Criteria:
                            
                                The exclusion criteria were unwillingness to participate or serious chronic disease. 
                            
                        
                
                            Research Purpose:
                            
                                To examine the feasibility and efficacy of a multifactorial intervention programme directed towards  ypercholesterolaemia, smoking, and diabetes mellitus in treated hypertensive patients after more than 3 years’ follow-up and to describe the incidence of cardiovascular complications. 
                            
                        
                
                            Blinding efforts:
                            
                                See Risk of Bias. 
                            
                        
                
                            Study Location:
                            
                                Sweden 
                            
                        
                
                            Source(s) of Funding:
                            
                                Government, Not-for-profit 
                            
                        
                
                            Please specify names of funders:
                            
                                This study was supported by grants from the Swedish Medical Research Council (B92-19X-0993 7-01A, B93-19X-0993 7-02B, B94-19X-0993 7-03A), the Swedish Heart and Lung Foundation and the Goteborg Medical Society. 
                            
                        


