HTN: Medical Nutrition Therapy (2022-24)
Author and Year:
Vamvakis A, Gkaliagkousi E, Lazaridis A, et al. 2020
PubMed ID:
Article Title:
Impact of Intensive Lifestyle Treatment (Diet Plus Exercise) on Endothelial and Vascular Function, Arterial Stiffness and Blood Pressure in Stage 1 Hypertension: Results of the HINTreat Randomized Controlled Trial.
Authors:
Vamvakis A, Gkaliagkousi E, Lazaridis A, Grammatikopoulou M, Triantafyllou A, Nikolaidou B, Koletsos N, Anyfanti P, Tzimos C, Zebekakis P, Douma S
Journal:
Nutrients
Year of publication:
2020
Volume:
12
Issue:
5
Page numbers:
Study Design:
Randomized Controlled Trial
Risk of Bias Assessment Rating:
High risk
Inclusion Criteria:
Inclusion criteria involved: (1) untreated stage I EH, (2) age > 18 years old and (3) agreement to participate.
Exclusion Criteria:
Exclusion criteria were: (1) diagnosis of secondary hypertension; (2) diabetes mellitus; (3) CVD (including history of coronary heart disease as evidenced by coronary angiography or a positive treadmill test, myocardial infarction, revascularization procedure, or stroke); (4) any known inflammatory condition; (5) malignancy; (6) or other significant Comorbidities affecting arterial BP; (7) treatment with antihypertensive agents or other significant medication,
including diuretics.
Research Purpose:
To investigate the effects of a six-month intensive lifestyle treatment (ILT) versus standard care, among patients with stage I essential hypertension.
Blinding efforts:
See Risk of Bias.
Study Location:
Greece
Source(s) of Funding:
University/Hospital, Not-for-profit
Please specify names of funders:
This research was funded by the of “Supporting Research and Academic Practices of the 3rd Internal Medicine Department”, grant number 91770, Aristotle University of Thessaloniki’s Research Committee.