HTN: Medical Nutrition Therapy (2022-24)
Author and Year:
Hinderliter A, Smith P, et al. 2021
PubMed ID:
Article Title:
Lifestyle Interventions Reduce the Need for Guideline-Directed Antihypertensive Medication.
Authors:
Hinderliter A, Smith P, Sherwood A, Blumenthal J
Journal:
American Journal of Hypertension
Year of publication:
2021
Volume:
34
Issue:
10
Page numbers:
1100-1107
Study Design:
Randomized Controlled Trial
Risk of Bias Assessment Rating:
Low risk
Inclusion Criteria:
Persons were eligible if they were not taking anti-hypertensive medication and had a mean systolic blood pressure (SBP) 130-159 or diastolic blood pressure (DBP) 85-99 mm Hg averaged over four separate BP screening visits. Other inclusion criteria included age 35 years or older, body mass index (BMI) of 25-40 kg/m2, and sedentary (i.e., not engaged in regular exercise).
Exclusion Criteria:
Other medical comorbidities that would preclude safe participation in the trial, including diabetes requiring insulin or oral hypoglycemic agents.
Research Purpose:
To examine hypertension treatment with the DASH diet alone, without exercise or weight loss (DASH-A), or the DASH diet combined with a behavioral weight management program including caloric restriction and
aerobic exercise (DASH-WM).
Blinding efforts:
See Risk of Bias
Study Location:
United States
Source(s) of Funding:
Government
Please specify names of funders:
Supported by grants from the National Heart, Lung, and Blood Institute (HL074103) and the General Clinical Research Center, National Institutes of Health (M01-RR-30). This publication was made possible by Grant Number 5UL1RR024128-03 from the National Center for Research Resources (NCRR), a component of the National Institutes of Health (NIH), and NIH Roadmap for Medical Research.