VN: Cardiovascular Disease Risk Factors (2024)

Author and Year:
Barnard N, Alwarith J, Rembert E, et al. 2022
PubMed ID:
Article Title:
A Mediterranean Diet and Low-Fat Vegan Diet to Improve Body Weight and Cardiometabolic Risk Factors: A Randomized, Cross-over Trial.
Barnard N, Alwarith J, Rembert E, Brandon L, Nguyen M, Goergen A, Horne T, do Nascimento G, Lakkadi K, Tura A, Holubkov R, Kahleova H
Journal of the American Nutrition Association
Year of publication:
Page numbers:
Study Design:
Randomized Crossover Trial
Risk of Bias Assessment Rating:
Some concerns
Inclusion Criteria:
Adults; BMI between 28-40
Exclusion Criteria:
Type 1 diabetes mellitus; smoking; alcohol or drug abuse; pregnancy; lactation; current use of a vegan or Mediterranean diet
Research Purpose:
The present study directly compared a Mediterranean and a vegan diet for their effects on weight and cardiometabolic parameters, using a cross-over design. Based on the findings of prior studies, it tested the hypothesis that, compared with a Mediterranean diet, a low-fat vegan diet results in greater changes in body weight, total and LDL-cholesterol concentrations, and insulin sensitivity.
Blinding efforts:
Study Location:
United States, George Washington University, Washington DC
Source(s) of Funding:
Please specify names of funders:
Physicians Committee for Responsible Medicine