VN: Cardiovascular Disease Risk Factors (2024)

Author and Year:
Burke L, Hudson A, Warziski M, et al. 2007
PubMed ID:
Article Title:
Effects of a vegetarian diet and treatment preference on biochemical and dietary variables in overweight and obese adults: a randomized clinical trial.
Burke L, Hudson A, Warziski M, Styn M, Music E, Elci O, Sereika S
American Journal of Clinical Nutrition
Year of publication:
Page numbers:
Study Design:
Randomized Controlled Trial
Risk of Bias Assessment Rating:
Some concerns
Inclusion Criteria:
Between 18 and 55 years of age; BMI of 27-43 kg/m2; willingness to be randomly assigned to 1 of 2 treatment-preference conditions and 1 of 2 dietary conditions; successful completion of a 5-day food dairy; willingness and ability to provide informed consent; no current medical condition requiring physician supervision of diet or physical activity; no physical limitation restricting exercise ability; not pregnant or planning to become pregnant during the 18-month study; no current treatment with a medication that might affect weight; alcohol intake not exceeding 4 drinks per day; no participation in a weight-loss program or use of a weight-loss medication within 6 months before the study enrollment; reported consuming of meat, poultry or fish in the past month.
Exclusion Criteria:
If they selected an equal preference for the 2 dietary options; diabetes
Research Purpose:
This study, called the PREFER study, was therefore conducted to determine the independent and combined effects of treatment preference and a standard behavioral treatment program with a calorie- and fat-restricted lactoovovegetarian diet (LOV-D) compared with a calorie- and fat-restricted standard omnivorous weight-loss diet (STD-D) on weight, serum lipids, insulin resistance, and macronutrient intake in overweight and obese adults. We also examined whether these outcomes differed among those who adhered to the vegetarian diet compared with those who did not.
Blinding efforts:
Study Location:
United States, University of Pittsburgh, Pittsburgh, PA
Source(s) of Funding:
Please specify names of funders: