VN: Cardiovascular Disease Risk Factors (2024)

Author and Year:
Leidy H,Carnelll N, et al. 2012
PubMed ID:
Article Title:
Higher protein intake preserves lean mass and satiety with weight loss in pre-obese and obese women.
Leidy H, Carnell N, Mattes R, Campbell W
Obesity (Silver Spring, Md.)
Year of publication:
Page numbers:
Study Design:
Randomized Controlled Trial
Risk of Bias Assessment Rating:
Some concerns
Inclusion Criteria:
1) Women 21 years of age or older; 2) BMI between 25 and 37 kg/m2; 3) not dieting and no weight loss or gain (>4.5 kg) within the last 6 months; 4) nonsmoking; 5) habitual/stable activity pattern within the last 3 months; 6) clinically normal blood profiles (specifically, normal liver and kidney functions; fasting blood glucose 110 mg/dL); and 7) nondiabetic.
Exclusion Criteria:
Not reported
Research Purpose:
The primary aim of this study was to examine the effects of a higher-protein (HP) vs. normal-protein (NP) energy restriction diet, matched for total fat intake, on body weight, body composition, appetite, mood state, and markers of cardiovascular and kidney functions. A secondary (retrospective) aim of this study was to determine whether obesity status, specifically pre-obese (POB) vs. obese (OB) classification, defined by the World Health Organization as a BMI of 25.0 to 29.9 kg/m2 for POB and a BMI of 30.0 to 39.9 kg/m2 for OB (Classes I and II) (17), differentially affects the energy restriction-induced changes in the parameters listed above.
Blinding efforts:
Not reported
Study Location:
Not reported
Source(s) of Funding:
Please specify names of funders:
National Pork Board