PDM: Prediabetes (2013)

PDM: Prediabetes (2013)

• Assessment
  In individuals with prediabetes, what is the impact of whole or refined grains, independent of weight loss, on glycemic-related outcomes (such as fasting blood glucose, random blood glucose, two-hour post-prandial blood glucose, A1C)?

  • Conclusion

    Limited research reports no significant impact of whole or refined grains, independent of weight loss, on fasting blood glucose or two-hour post-prandial blood glucose in individuals with prediabetes.

    Additional intervention studies are needed to ascertain the effect of whole or refined grains on glycemic-related outcomes in individuals with prediabetes.

  • Grade: III
    • Grade I means there is Good/Strong evidence supporting the statement;
    • Grade II is Fair;
    • Grade III is Limited/Weak;
    • Grade IV is Expert Opinion Only;
    • Grade V is Not Assignable.
    • High (A) means we are very confident that the true effect lies close to that of the estimate of the effect;
    • Moderate (B) means we are moderately confident in the effect estimate;
    • Low (C) means our confidence in the effect estimate is limited;
    • Very Low (D) means we have very little confidence in the effect estimate.
    • Ungraded means a grade is not assignable.
  • Evidence Summary: In individuals with prediabetes, what is the impact of whole or refined grains, independent of weight loss, on glycemic-related outcomes (such as fasting blood glucose, random blood glucose, two-hour post-prandial blood glucose, A1C)?
    • Detail
    • Quality Rating Summary
      For a summary of the Quality Rating results, click here.
    • Worksheets
      • Lankinen M, Schwab U, Kolehmainen M, Paananen J, Poutanen K, Mykkanen H, Seppanen-Laakso T, Gylling H, Uusitupa M, Oresic M. Whole grain products, fish and bilberries alter glucose and lipid metabolism in a randomized, controlled trial: The Sysdimet study. PLos One. 2011; 6(8): e22646.
  • Search Plan and Results: PDM: Whole and Refined Grains and Prediabetes 2012
     
• Intervention
  In individuals with prediabetes, what is the impact of whole or refined grains, independent of weight loss, on lipid outcomes (TG, HDL)?

  • Conclusion

    There were no studies identified to evaluate the impact of whole or refined grains, independent of weight loss, on lipid outcomes in individuals with prediabetes.

    Intervention studies are needed to ascertain the effect of whole or refined grains on lipid outcomes in individuals with prediabetes.

  • Grade: V
    • Grade I means there is Good/Strong evidence supporting the statement;
    • Grade II is Fair;
    • Grade III is Limited/Weak;
    • Grade IV is Expert Opinion Only;
    • Grade V is Not Assignable.
    • High (A) means we are very confident that the true effect lies close to that of the estimate of the effect;
    • Moderate (B) means we are moderately confident in the effect estimate;
    • Low (C) means our confidence in the effect estimate is limited;
    • Very Low (D) means we have very little confidence in the effect estimate.
    • Ungraded means a grade is not assignable.
  • Search Plan and Results: PDM: Whole and Refined Grains and Prediabetes 2012
     
  In individuals with prediabetes, what is the impact of whole or refined grains, independent of weight loss, on anthropometric outcomes (WC, WHR)?

  • Conclusion

    There were no studies identified to evaluate the impact of whole or refined grains, independent of weight loss, on anthropometric outcomes in individuals with prediabetes.

    Intervention studies are needed to ascertain the effect of whole or refined grains on anthropometric outcomes in individuals with prediabetes.

  • Grade: V
    • Grade I means there is Good/Strong evidence supporting the statement;
    • Grade II is Fair;
    • Grade III is Limited/Weak;
    • Grade IV is Expert Opinion Only;
    • Grade V is Not Assignable.
    • High (A) means we are very confident that the true effect lies close to that of the estimate of the effect;
    • Moderate (B) means we are moderately confident in the effect estimate;
    • Low (C) means our confidence in the effect estimate is limited;
    • Very Low (D) means we have very little confidence in the effect estimate.
    • Ungraded means a grade is not assignable.
  • Search Plan and Results: PDM: Whole and Refined Grains and Prediabetes 2012
     
  In individuals with prediabetes, what is the impact of whole or refined grains, independent of weight loss, on blood pressure?

  • Conclusion

    There were no studies identified to evaluate the impact of whole or refined grains, independent of weight loss, on blood pressure in individuals with prediabetes.

    Intervention studies are needed to ascertain the effect of whole or refined grains on blood pressure in individuals with prediabetes.

  • Grade: V
    • Grade I means there is Good/Strong evidence supporting the statement;
    • Grade II is Fair;
    • Grade III is Limited/Weak;
    • Grade IV is Expert Opinion Only;
    • Grade V is Not Assignable.
    • High (A) means we are very confident that the true effect lies close to that of the estimate of the effect;
    • Moderate (B) means we are moderately confident in the effect estimate;
    • Low (C) means our confidence in the effect estimate is limited;
    • Very Low (D) means we have very little confidence in the effect estimate.
    • Ungraded means a grade is not assignable.
  • Search Plan and Results: PDM: Whole and Refined Grains and Prediabetes 2012