PDM: Metabolic Syndrome (2013)

PDM: Metabolic Syndrome (2013)

• Assessment
  In adults with metabolic syndrome, what is the impact of glycemic index/load, independent of weight loss, on lipid outcomes (HDL, TG)?

  • Conclusion

    One feeding study reports no significant effect of glycemic index/load on triglyceride or HDL-cholesterol levels in adults with metabolic syndrome.

    Intervention studies are needed to ascertain an effect of glycemic index/load on lipid outcomes in adults with metabolic syndrome with or without meeting the metabolic syndrome criteria for lipid levels.

    
     

     

     

     

     

     

  • Grade: III
    • Grade I means there is Good/Strong evidence supporting the statement;
    • Grade II is Fair;
    • Grade III is Limited/Weak;
    • Grade IV is Expert Opinion Only;
    • Grade V is Not Assignable.
    • High (A) means we are very confident that the true effect lies close to that of the estimate of the effect;
    • Moderate (B) means we are moderately confident in the effect estimate;
    • Low (C) means our confidence in the effect estimate is limited;
    • Very Low (D) means we have very little confidence in the effect estimate.
    • Ungraded means a grade is not assignable.
  • Evidence Summary: In adults with metabolic syndrome, what is the impact of glycemic index/load, independent of weight loss, on lipid outcomes (HDL, TG)?
    • Detail
    • Quality Rating Summary
      For a summary of the Quality Rating results, click here.
    • Worksheets
      • Konig D, Theis S, Kozianowski G, Berg A. Postprandial substrate use in overweight subjects with the metabolic syndrome after isomaltulose (Palatinose™) ingestion. Nutrition. 2012; 28(6): 651-656.
  • Search Plan and Results: PDM: Glycemic Index/Load and Metabolic Syndrome 2012
     
  In adults with metabolic syndrome, what is the impact of glycemic index/load, independent of weight loss, on glycemic-related outcomes (such as fasting blood glucose, random blood glucose, 2-hour post prandial blood glucose, A1C)?

  • Conclusion

    Two feeding studies regarding the impact of glycemic index/load reported a significant decrease in postprandial glycemic outcomes in adults with metabolic syndrome.

    Intervention studies are needed to ascertain an effect of glycemic index/load on glycemic-related outcomes in adults with metabolic syndrome with or without meeting the metabolic syndrome criteria for impaired glucose tolerance and/or impaired fasting glucose.

     

  • Grade: III
    • Grade I means there is Good/Strong evidence supporting the statement;
    • Grade II is Fair;
    • Grade III is Limited/Weak;
    • Grade IV is Expert Opinion Only;
    • Grade V is Not Assignable.
    • High (A) means we are very confident that the true effect lies close to that of the estimate of the effect;
    • Moderate (B) means we are moderately confident in the effect estimate;
    • Low (C) means our confidence in the effect estimate is limited;
    • Very Low (D) means we have very little confidence in the effect estimate.
    • Ungraded means a grade is not assignable.
  • Evidence Summary: In adults with metabolic syndrome, what is the impact of glycemic index/load, independent of weight loss, on glycemic-related outcomes (such as fasting blood glucose, random blood glucose, two-hour post prandial blood glucose, A1C)?
    • Detail
    • Quality Rating Summary
      For a summary of the Quality Rating results, click here.
    • Worksheets
      • Konig D, Muser K, Berg A, Deibert P. Fuel selection and appetite-regulating hormones after intake of a soy protein-based meal replacement. Nutrition. 2012; 28(1): 35-39.
      • Konig D, Theis S, Kozianowski G, Berg A. Postprandial substrate use in overweight subjects with the metabolic syndrome after isomaltulose (Palatinose™) ingestion. Nutrition. 2012; 28(6): 651-656.
  • Search Plan and Results: PDM: Glycemic Index/Load and Metabolic Syndrome 2012
     
• Intervention
  In adults with metabolic syndrome, what is the impact of glycemic index/load, independent of weight loss, on anthropometric outcomes (WC, WHR)?

  • Conclusion

    There were no studies identified to evaluate the impact of glycemic index/load on anthropometric outcomes in adults with metabolic syndrome.

    Intervention studies are needed to ascertain an effect of glycemic index/load on anthropometric outcomes in adults with metabolic syndrome with or without meeting the metabolic syndrome criteria for anthropometric measures.

  • Grade: V
    • Grade I means there is Good/Strong evidence supporting the statement;
    • Grade II is Fair;
    • Grade III is Limited/Weak;
    • Grade IV is Expert Opinion Only;
    • Grade V is Not Assignable.
    • High (A) means we are very confident that the true effect lies close to that of the estimate of the effect;
    • Moderate (B) means we are moderately confident in the effect estimate;
    • Low (C) means our confidence in the effect estimate is limited;
    • Very Low (D) means we have very little confidence in the effect estimate.
    • Ungraded means a grade is not assignable.
  • Search Plan and Results: PDM: Glycemic Index/Load and Metabolic Syndrome 2012
     
  In adults with metabolic syndrome, what is the impact of glycemic index/load, independent of weight loss, on blood pressure?

  • Conclusion

    There were no studies identified to evaluate the impact of glycemic index/load on blood pressure in adults with metabolic syndrome.

    Intervention studies are needed to ascertain an effect of glycemic index/load on blood pressure in adults with metabolic syndrome with or without meeting the metabolic syndrome criteria for blood pressure.

  • Grade: V
    • Grade I means there is Good/Strong evidence supporting the statement;
    • Grade II is Fair;
    • Grade III is Limited/Weak;
    • Grade IV is Expert Opinion Only;
    • Grade V is Not Assignable.
    • High (A) means we are very confident that the true effect lies close to that of the estimate of the effect;
    • Moderate (B) means we are moderately confident in the effect estimate;
    • Low (C) means our confidence in the effect estimate is limited;
    • Very Low (D) means we have very little confidence in the effect estimate.
    • Ungraded means a grade is not assignable.
  • Search Plan and Results: PDM: Glycemic Index/Load and Metabolic Syndrome 2012
     
  In adults with metabolic syndrome, what is the impact of glycemic index/load, independent of weight loss, on renal outcomes?

  • Conclusion

    There were no studies identified to evaluate the impact of glycemic index/load on renal outcomes in adults with metabolic syndrome.

    Intervention studies are needed to ascertain an effect of glycemic index/load on renal outcomes in adults with metabolic syndrome with or without meeting the metabolic syndrome criteria for renal measures.

  • Grade: V
    • Grade I means there is Good/Strong evidence supporting the statement;
    • Grade II is Fair;
    • Grade III is Limited/Weak;
    • Grade IV is Expert Opinion Only;
    • Grade V is Not Assignable.
    • High (A) means we are very confident that the true effect lies close to that of the estimate of the effect;
    • Moderate (B) means we are moderately confident in the effect estimate;
    • Low (C) means our confidence in the effect estimate is limited;
    • Very Low (D) means we have very little confidence in the effect estimate.
    • Ungraded means a grade is not assignable.
  • Search Plan and Results: PDM: Glycemic Index/Load and Metabolic Syndrome 2012