Chronic Kidney Disease

CKD: Potassium (2018)

• Intervention
  What is the effect of dietary potassium intake on mortality in adults with CKD 1-5D and post-transplant?

  • Conclusion

    In CKD hemodialysis patients, higher dietary potassium intake was associated with greater mortality risk in one study.

  • Grade: III
    • Grade I means there is Good/Strong evidence supporting the statement;
    • Grade II is Fair;
    • Grade III is Limited/Weak;
    • Grade IV is Expert Opinion Only;
    • Grade V is Not Assignable.
    • High (A) means we are very confident that the true effect lies close to that of the estimate of the effect;
    • Moderate (B) means we are moderately confident in the effect estimate;
    • Low (C) means our confidence in the effect estimate is limited;
    • Very Low (D) means we have very little confidence in the effect estimate.
    • Ungraded means a grade is not assignable.
  • Evidence Summary: What is the effect of dietary potassium intake on mortality in adults with CKD 1-5D and post-transplant?
    • Detail
    • Quality Rating Summary
      For a summary of the Quality Rating results, click here.
    • Worksheets
      • Noori N, Kalantar-Zadeh K, Kovesdy C, Murali S, Bross R, Nissenson A, Kopple J. Dietary potassium intake and mortality in long-term hemodialysis patients. American Journal of Kidney Diseases : the official journal of the National Kidney Foundation 2010; 56:338-47
  • Search Plan and Results: CKD: Electrolytes: Potassium (2018)
     
  What is the effect of urinary potassium excretion on mortality in adults with CKD 1-5D and post-transplant?

  • Conclusion

    In CKD pre-dialysis patients, one study observed a significant association between urinary potassium excretion and mortality, while another study found no such association.

  • Grade: II
    • Grade I means there is Good/Strong evidence supporting the statement;
    • Grade II is Fair;
    • Grade III is Limited/Weak;
    • Grade IV is Expert Opinion Only;
    • Grade V is Not Assignable.
    • High (A) means we are very confident that the true effect lies close to that of the estimate of the effect;
    • Moderate (B) means we are moderately confident in the effect estimate;
    • Low (C) means our confidence in the effect estimate is limited;
    • Very Low (D) means we have very little confidence in the effect estimate.
    • Ungraded means a grade is not assignable.
  • Evidence Summary: What is the effect of urinary potassium excretion on mortality in adults with CKD 1-5D and post-transplant?
    • Detail
    • Quality Rating Summary
      For a summary of the Quality Rating results, click here.
    • Worksheets
      • He J, Mills K, Appel L, Yang W, Chen J, Lee B, Rosas S, Porter A, Makos G, Weir M, Hamm L, Kusek J. Urinary Sodium and Potassium Excretion and CKD Progression. Journal of the American Society of Nephrology 2016; 27:1202-12
      • Leonberg-Y AK, Tighiouart H, Levey AS, Beck GJ, Sarnak MJ.. Urine potassium excretion, kidney failure, and mortality in CKD. American Journal of Kidney Disease 2016; 69:341-349
  • Search Plan and Results: CKD: Electrolytes: Potassium (2018)
     
  What is the effect of urinary potassium excretion on CKD progression in adults with CKD 1-5D and post-transplant?

  • Conclusion

    In pre-dialysis patients, one study observed a positive association between urinary potassium excretion and CKD progression (defined as incident end-stage renal disease (ESRD) or halving of eGFR from baseline) while the other one found no significant association in either direction.

  • Grade: II
    • Grade I means there is Good/Strong evidence supporting the statement;
    • Grade II is Fair;
    • Grade III is Limited/Weak;
    • Grade IV is Expert Opinion Only;
    • Grade V is Not Assignable.
    • High (A) means we are very confident that the true effect lies close to that of the estimate of the effect;
    • Moderate (B) means we are moderately confident in the effect estimate;
    • Low (C) means our confidence in the effect estimate is limited;
    • Very Low (D) means we have very little confidence in the effect estimate.
    • Ungraded means a grade is not assignable.
  • Evidence Summary: What is the effect of urinary potassium excretion on CKD progression in adults with CKD 1-5D and post-transplant?
    • Detail
    • Quality Rating Summary
      For a summary of the Quality Rating results, click here.
    • Worksheets
      • He J, Mills K, Appel L, Yang W, Chen J, Lee B, Rosas S, Porter A, Makos G, Weir M, Hamm L, Kusek J. Urinary Sodium and Potassium Excretion and CKD Progression. Journal of the American Society of Nephrology 2016; 27:1202-12
      • Leonberg-Y AK, Tighiouart H, Levey AS, Beck GJ, Sarnak MJ.. Urine potassium excretion, kidney failure, and mortality in CKD. American Journal of Kidney Disease 2016; 69:341-349
  • Search Plan and Results: CKD: Electrolytes: Potassium (2018)