CKD: Nutritional Status: Hand Grip Strength (2018)
Is there evidence to support the use of the hand-grip strength for assessing nutritional status in adults with CKD 1-5D and post-transplant?
Handgrip strength (HGS) was a valid measure of nutritional status compared to malnutrition inflammation score (MIS) in hemodialysis patients (one study) and was significantly negatively associated with MIS in pre-dialysis patients (one study), but results may vary according to adjustment for confounding variables. HGS was correlated with lean body mass assessed by other methods, but there was no correlation with other body composition or nutritional status markers in peritoneal dialysis (PD) patients (one study). In dialysis patients, HGS had higher correlations with nutritional status and inflammatory markers and was more predictive of mortality than muscle mass measured by DEXA (one study).
- Grade I means there is Good/Strong evidence supporting the statement;
- Grade II is Fair;
- Grade III is Limited/Weak;
- Grade IV is Expert Opinion Only;
- Grade V is Not Assignable.
- High (A) means we are very confident that the true effect lies close to that of the estimate of the effect;
- Moderate (B) means we are moderately confident in the effect estimate;
- Low (C) means our confidence in the effect estimate is limited;
- Very Low (D) means we have very little confidence in the effect estimate.
- Ungraded means a grade is not assignable.
Evidence Summary: Is there evidence to support the use of the hand-grip strength for assessing nutritional status in adults with CKD 1-5D and post-transplant?
- Quality Rating Summary
For a summary of the Quality Rating results, click here.
- Amparo F, Cordeiro A, Carrero J, Cuppari L, Lindholm B, Amodeo C, Kamimura M. Malnutrition-inflammation score is associated with handgrip strength in nondialysis-dependent chronic kidney disease patients. Journal of Renal Nutrition : the official journal of the Council on Renal Nutrition of the National Kidney Foundation 2013; 23:283-7
- Hasheminejad N, Namdari M, Mahmoodi M, Bahrampour A, Azmandian J. Association of Handgrip Strength With Malnutrition-Inflammation Score as an Assessment of Nutritional Status in Hemodialysis Patients.. Iranian Journal of Kidney Diseases 2016; 10:30-5
- Isoyama N, Qureshi A, Avesani C, Lindholm B, Bàràny P, Heimbürger O, Cederholm T, Stenvinkel P, Carrero J. Comparative associations of muscle mass and muscle strength with mortality in dialysis patients. Clinical Journal of the American Society of Nephrology 2014; 9:1720-8
- Konings C, Kooman J, Schonck M, van Kreel B, Heidendal G, Cheriex E, van der Sande F, Leunissen K. Influence of fluid status on techniques used to assess body composition in peritoneal dialysis patients. Peritoneal dialysis international : journal of the International Society for Peritoneal Dialysis 2003; 23:184-90
- Silva L, Matos C, Lopes G, Martins M, Martins M, Arias L, Pisoni R, Lopes A. Handgrip strength as a simple indicator of possible malnutrition and inflammation in men and women on maintenance hemodialysis. Journal of Renal Nutrition : the official journal of the Council on Renal Nutrition of the National Kidney Foundation 2011; 21:235-45
Search Plan and Results: CKD: Assessment: Hand Grip Strength (2018)