CRDA: Lipid Outcomes (2023)
Author and Year:
Pedersen E, Jesudason D, Clifton P 2014
PubMed ID:
Article Title:
High protein weight loss diets in obese subjects with type 2 diabetes mellitus.
Authors:
Pedersen E, Jesudason D, Clifton P
Journal:
Nutrition, Metabolism, and Cardiovascular Diseases
Year of publication:
2014
Volume:
24
Issue:
5
Page numbers:
554-562
Study Design:
Randomized Controlled Trial
Risk of Bias Assessment Rating:
Some concerns
Inclusion Criteria:
BMI >/= 27 kg/m2; type 2 diabetes; 18-75 years; albuminuria(30-600 mg/24 h or an albumin to creatinine ratio of 3.0-60.0 mg/mmol, with an estimated glomerular filtration rate (eGFR) of >40 ml/min/1.73 m2)
Exclusion Criteria:
Impaired kidney function not due to diabetes.
Research Purpose:
Our objective was to compare the effect on metabolic parameters of a high protein to carbohydrate ratio weight loss diet compared to a standard protein weight loss diet in volunteers with type 2 diabetes and an increased risk of CVD because of their albuminuria. We also wanted to investigate the relationship between changes in CGMS glucose values and markers of renal function, HbA1c, serum lipids and blood pressure to determine if using CGMS enhanced our understanding of the metabolic changes.
Blinding efforts:
Study Location:
Adelaide, Australia
Source(s) of Funding:
Government
Please specify names of funders:
Commonwealth Scientific and Industrial Research Organisation (CSIRO)