NPA-GP: Glucose Outcomes (2021)

Author and Year:
Rouman C, Feskens E, et al, 2011
PubMed ID:
Article Title:
Predictors of lifestyle intervention outcome and dropout: the SLIM study.
Roumen C, Feskens E, Corpeleijn E, Mensink M, Saris W, Blaak E
European Journal of Clinical Nutrition
Year of publication:
Page numbers:
Study Design:
Randomized Controlled Trial
Risk of Bias Assessment Rating:
Some concerns
Inclusion Criteria:
Mean 2 hour glucose concentration of both oral glucose tolerance tests between 7.8 and 12.5 mmol/l; fasting glucose concentration /= 25 kg/m2; white; age 40- 70 years.
Exclusion Criteria:
Known diabetes mellitus; mean 2-h blood glucose >12.5 mmol/L ; mean fasting blood glucose >7.8 mmol/L; any chronic illness that makes 5-years survival improbable or that interferers with glucose tolerance or that makes participation in a lifestyle-intervention impossible; medication known to interfere with glucose tolerance; participation in a regular vigorous exercise and/or diet program.
Research Purpose:
To assess the long-term results of a lifestyle intervention aimed at improving glucose tolerance in a Dutch population at high risk for type 2 diabetes.
Blinding efforts:
Study Location:
Maastricht, The Netherlands
Source(s) of Funding:
Government, Not-for-profit
Please specify names of funders:
Dutch Diabetes Research Foundation the Netherlands Organization for Scientific Research
Trial Name if applicable:
The Study on Lifestyle Intervention and Impaired glucose tolerance Maastricht (SLIM); NCT00381186