Gestational Diabetes

GDM: Ketone Testing (2001)

Ketone testing (Gestational Diabetes Mellitus 2001)

Gestational Diabetes Medical Nutrition Therapy Protocol (2001)

The ADA 2001 Gestational Diabetes MNT Evidence-based guide for practice was originally published in a compact disk (CD) format. This 2001 project was published to the online Evidence Analysis Library for the benefit of ADA members, even though it does not follow the current online format and may be missing some of the components. (The current evidence analysis projects include the following components: question, conclusion, grade, search plan and results, evidence summary, overview table, worksheets, and quality check lists.)

• Assessment
  Gestational Diabetes Mellitus Conclusion Statements: Ketone Testing (2001 CD)

  • Conclusion

    Ketonemia and ketonuria during GDM is positively associated with a lower IQ in offspring in case control and cohort studies. Ketone testing is an important part of self-monitoring and aids in adjusting calorie level, carbohydrate distribution and physical activity.

  • Grade: II
    • Grade I means there is Good/Strong evidence supporting the statement;
    • Grade II is Fair;
    • Grade III is Limited/Weak;
    • Grade IV is Expert Opinion Only;
    • Grade V is Not Assignable.
    • High (A) means we are very confident that the true effect lies close to that of the estimate of the effect;
    • Moderate (B) means we are moderately confident in the effect estimate;
    • Low (C) means our confidence in the effect estimate is limited;
    • Very Low (D) means we have very little confidence in the effect estimate.
    • Ungraded means a grade is not assignable.
  • Evidence Summary: Gestational Diabetes and Ketone Testing (2001 CD)
    • Detail
    • Quality Rating Summary
      For a summary of the Quality Rating results, click here.
    • Worksheets
      • Butte NF.  Carbohydrate and lipid metabolism in pregnancy:  normal compared with gestational diabetes mellitus.  Am J Clin Nutr 2000;71(suppl):1256S-1261S.
      • Churchill JA, Berendes HW, Nemore J.  Neuropsychological deficits in children of diabetic mothers.  Am J Obstet Gynecol 1969; 105:257-268.
      • Metzger BE, Coustan DR.  Summary and recommendations of the Fourth International Workshop-Conference on Gestational Diabetes Mellitus.  The Organizing Committee.  Diabetes Care 1998;21 Suppl 2:B161-167.
      • Naeye RL, Chez RA.  Effects of maternal acetonuria and low pregnancy weight gain on children's psychomotor development.  Am J Obstet Gynecol 1981;139:189-193. 
      • Rizzo T, Metzger BE, Burns WJ, Burns K.  Correlations between antepartum maternal metabolism and intelligence of offspring.  NEJM 1991;325(13):911-916.