VN: Cardiovascular Disease (2024)

Author and Year:
Djekic D, Shi L, Brolin H, et al. 2020
PubMed ID:
Article Title:
Effects of a Vegetarian Diet on Cardiometabolic Risk Factors, Gut Microbiota, and Plasma Metabolome in Subjects With Ischemic Heart Disease: A Randomized, Crossover Study.
Djekic D, Shi L, Brolin H, Carlsson F, Särnqvist C, Savolainen O, Cao Y, Bäckhed F, Tremaroli V, Landberg R, Frøbert O
Journal of the American Heart Association
Year of publication:
Page numbers:
Study Design:
Randomized Crossover Trial
Risk of Bias Assessment Rating:
Some concerns
Inclusion Criteria:
Patients with ischemic heart disease who were treated with percutaneous coronary intervention and receiving optimal medical therapy. Age>18 years, stable ischemic heart disease, percutaneous coronary intervention conducted >1 month before study initiation and optimal medical therapy including aspirin and cholesterol-lowering drugs
Exclusion Criteria:
Age <18 years, unstable coronary disease, percutaneous coronary intervention treatment during the preceding 30 days, inability to provide informed consent, already following a vegetarian or vegan diet, vitamin B deficiency, known food allergy, previous bariatric surgery, or life expectancy < 1 year
Research Purpose:
To investigate effects of a vegetarian diet on CVD risk factors in subjects with a history of ischemic heart disease treated by percutaneous coronary intervention, compared with an isocaloric meat diet
Blinding efforts:
Not applicable
Study Location:
Örebro University Hospital, Örebro, Sweden
Source(s) of Funding:
Government, University/Hospital
Please specify names of funders:
Region Örebro County through Funding for Medical Training. Grants from The Swedish Research Council, the Swedish Research Council Formas, and the Chalmers Foundation.