VN: Type 2 Diabetes Mellitus (2024)

Intervention
In adults with type 2 diabetes mellitus, what are the effects of vegetarian diets on hemoglobin A1C?
- Conclusion
  In adults with type 2 diabetes mellitus, vegetarian and vegan diets likely reduce HbA1c compared to therapeutic or non-therapeutic non-vegetarian diets.
- Grade: Moderate (B)
  - Grade I means there is Good/Strong evidence supporting the statement;
  - Grade II is Fair;
  - Grade III is Limited/Weak;
  - Grade IV is Expert Opinion Only;
  - Grade V is Not Assignable.
  - High (A) means we are very confident that the true effect lies close to that of the estimate of the effect;
  - Moderate (B) means we are moderately confident in the effect estimate;
  - Low (C) means our confidence in the effect estimate is limited;
  - Very Low (D) means we have very little confidence in the effect estimate.
  - Ungraded means a grade is not assignable.
- Evidence Summary: In adults with type 2 diabetes mellitus, what are the effects of vegetarian diets on hemoglobin A1C?
- Search Plan and Results: Vegetarian Nutrition and Disease Management (2024)
In adults with type 2 diabetes mellitus, what are the effects of vegetarian diets on fasting blood glucose?
- Conclusion
  In adults with type 2 diabetes mellitus, vegetarian and vegan diets may have little or no effect on fasting blood glucose concentrations compared to therapeutic or non-therapeutic non-vegetarian diets.
- Grade: Low (C)
  - Grade I means there is Good/Strong evidence supporting the statement;
  - Grade II is Fair;
  - Grade III is Limited/Weak;
  - Grade IV is Expert Opinion Only;
  - Grade V is Not Assignable.
  - High (A) means we are very confident that the true effect lies close to that of the estimate of the effect;
  - Moderate (B) means we are moderately confident in the effect estimate;
  - Low (C) means our confidence in the effect estimate is limited;
  - Very Low (D) means we have very little confidence in the effect estimate.
  - Ungraded means a grade is not assignable.
- Evidence Summary: In adults with type 2 diabetes mellitus, what are the effects of vegetarian diets on fasting blood glucose?
- Search Plan and Results: Vegetarian Nutrition and Disease Management (2024)
In adults with type 2 diabetes mellitus, what are the effects of vegetarian diets on fasting plasma insulin?
- Conclusion
  In adults with type 2 diabetes mellitus, there was no difference in fasting plasma insulin between participants following a lacto-ovo vegetarian diet compared to a therapeutic diet for 24 weeks.
- Grade: Very Low (D)
  - Grade I means there is Good/Strong evidence supporting the statement;
  - Grade II is Fair;
  - Grade III is Limited/Weak;
  - Grade IV is Expert Opinion Only;
  - Grade V is Not Assignable.
  - High (A) means we are very confident that the true effect lies close to that of the estimate of the effect;
  - Moderate (B) means we are moderately confident in the effect estimate;
  - Low (C) means our confidence in the effect estimate is limited;
  - Very Low (D) means we have very little confidence in the effect estimate.
  - Ungraded means a grade is not assignable.
- Evidence Summary: In adults with type 2 diabetes mellitus, what are the effects of vegetarian diets on fasting plasma insulin?
- Search Plan and Results: Vegetarian Nutrition and Disease Management (2024)
In adults with type 2 diabetes mellitus, what are the effects of vegetarian diets on insulin sensitivity?
- Conclusion
  In adults with type 2 diabetes mellitus, lacto-ovo vegetarian diets may improve metabolic clearance rate of glucose (insulin sensitivity) compared to a therapeutic diet after 24 weeks, but evidence is uncertain.
- Grade: Very Low (D)
  - Grade I means there is Good/Strong evidence supporting the statement;
  - Grade II is Fair;
  - Grade III is Limited/Weak;
  - Grade IV is Expert Opinion Only;
  - Grade V is Not Assignable.
  - High (A) means we are very confident that the true effect lies close to that of the estimate of the effect;
  - Moderate (B) means we are moderately confident in the effect estimate;
  - Low (C) means our confidence in the effect estimate is limited;
  - Very Low (D) means we have very little confidence in the effect estimate.
  - Ungraded means a grade is not assignable.
- Evidence Summary: In adults with type 2 diabetes mellitus, what are the effects of vegetarian diets on insulin sensitivity?
- Search Plan and Results: Vegetarian Nutrition and Disease Management (2024)
In adults with type 2 diabetes mellitus, what are the effects of vegetarian diets on diabetes medication?
- Conclusion
  In adults with type 2 diabetes mellitus, evidence on the effect of vegetarian diets compared to non-vegetarian diets was mixed but does suggest a benefit of vegetarian diets on diabetes medication needs compared to therapeutic or non-therapeutic non-vegetarian diets.
- Grade: Low (C)
  - Grade I means there is Good/Strong evidence supporting the statement;
  - Grade II is Fair;
  - Grade III is Limited/Weak;
  - Grade IV is Expert Opinion Only;
  - Grade V is Not Assignable.
  - High (A) means we are very confident that the true effect lies close to that of the estimate of the effect;
  - Moderate (B) means we are moderately confident in the effect estimate;
  - Low (C) means our confidence in the effect estimate is limited;
  - Very Low (D) means we have very little confidence in the effect estimate.
  - Ungraded means a grade is not assignable.
- Evidence Summary: In adults with type 2 diabetes mellitus, what are the effects of vegetarian diets on diabetes medication?
- Search Plan and Results: Vegetarian Nutrition and Disease Management (2024)
In adults with type 2 diabetes mellitus, what are the effects of vegetarian diets on body mass index?
- Conclusion
  In adults with type 2 diabetes mellitus, vegetarian and vegan diets likely reduce body mass index compared to therapeutic or non-therapeutic non-vegetarian diets.
- Grade: Moderate (B)
  - Grade I means there is Good/Strong evidence supporting the statement;
  - Grade II is Fair;
  - Grade III is Limited/Weak;
  - Grade IV is Expert Opinion Only;
  - Grade V is Not Assignable.
  - High (A) means we are very confident that the true effect lies close to that of the estimate of the effect;
  - Moderate (B) means we are moderately confident in the effect estimate;
  - Low (C) means our confidence in the effect estimate is limited;
  - Very Low (D) means we have very little confidence in the effect estimate.
  - Ungraded means a grade is not assignable.
- Evidence Summary: In adults with type 2 diabetes mellitus, what are the effects of vegetarian diets on body mass index?
- Search Plan and Results: Vegetarian Nutrition and Disease Management (2024)
In adults with type 2 diabetes mellitus, what are the effects of vegetarian diets on LDL cholesterol?
- Conclusion
  In adults with type 2 diabetes mellitus, vegetarian diets may have no effect on low-density lipoprotein (LDL) cholesterol concentrations compared to therapeutic or non-therapeutic non-vegetarian diets.
- Grade: Low (C)
  - Grade I means there is Good/Strong evidence supporting the statement;
  - Grade II is Fair;
  - Grade III is Limited/Weak;
  - Grade IV is Expert Opinion Only;
  - Grade V is Not Assignable.
  - High (A) means we are very confident that the true effect lies close to that of the estimate of the effect;
  - Moderate (B) means we are moderately confident in the effect estimate;
  - Low (C) means our confidence in the effect estimate is limited;
  - Very Low (D) means we have very little confidence in the effect estimate.
  - Ungraded means a grade is not assignable.
- Evidence Summary: In adults with type 2 diabetes mellitus, what are the effects of vegetarian diets on LDL cholesterol?
- Search Plan and Results: Vegetarian Nutrition and Disease Management (2024)
In adults with type 2 diabetes mellitus, what are the effects of vegetarian diets on quality of life?
- Conclusion
  In adults with type 2 diabetes mellitus, the effect of vegetarian, compared to non-vegetarian, diets on quality of life is uncertain.
- Grade: Very Low (D)
  - Grade I means there is Good/Strong evidence supporting the statement;
  - Grade II is Fair;
  - Grade III is Limited/Weak;
  - Grade IV is Expert Opinion Only;
  - Grade V is Not Assignable.
  - High (A) means we are very confident that the true effect lies close to that of the estimate of the effect;
  - Moderate (B) means we are moderately confident in the effect estimate;
  - Low (C) means our confidence in the effect estimate is limited;
  - Very Low (D) means we have very little confidence in the effect estimate.
  - Ungraded means a grade is not assignable.
- Evidence Summary: In adults with type 2 diabetes mellitus, what are the effects of vegetarian diets on quality of life?
- Search Plan and Results: Vegetarian Nutrition and Disease Management (2024)
In adults with type 2 diabetes mellitus, what is are the effects of vegetarian diets on cardiovascular disease, hypertension, kidney disease and retinopathy incidence and mortality?
- Conclusion
  There were no studies available examining the effects of vegetarian diets on cardiovascular disease, hypertension, kidney disease and retinopathy incidence and mortality in adults with type 2 diabetes mellitus.
- Grade: Ungraded
  - Grade I means there is Good/Strong evidence supporting the statement;
  - Grade II is Fair;
  - Grade III is Limited/Weak;
  - Grade IV is Expert Opinion Only;
  - Grade V is Not Assignable.
  - High (A) means we are very confident that the true effect lies close to that of the estimate of the effect;
  - Moderate (B) means we are moderately confident in the effect estimate;
  - Low (C) means our confidence in the effect estimate is limited;
  - Very Low (D) means we have very little confidence in the effect estimate.
  - Ungraded means a grade is not assignable.
In adults with type 2 diabetes mellitus, what are adverse effects from vegetarian diets?
- Conclusion
  In adults with type 2 diabetes mellitus, evidence suggests there are no adverse events from following lacto-ovo vegetarian or vegan diets, but evidence is uncertain.
- Grade: Low (C)
  - Grade I means there is Good/Strong evidence supporting the statement;
  - Grade II is Fair;
  - Grade III is Limited/Weak;
  - Grade IV is Expert Opinion Only;
  - Grade V is Not Assignable.
  - High (A) means we are very confident that the true effect lies close to that of the estimate of the effect;
  - Moderate (B) means we are moderately confident in the effect estimate;
  - Low (C) means our confidence in the effect estimate is limited;
  - Very Low (D) means we have very little confidence in the effect estimate.
  - Ungraded means a grade is not assignable.
- Evidence Summary: In adults with type 2 diabetes mellitus, what are adverse effects from vegetarian diets?
- Search Plan and Results: Vegetarian Nutrition and Disease Management (2024)