VN: Cardiovascular Disease Risk Factors (2024)

Author and Year:
Jenkins D, Wong J, Kendall C, et al. 2014
PubMed ID:
Article Title:
Effect of a 6-month vegan low-carbohydrate ('Eco-Atkins') diet on cardiovascular risk factors and body weight in hyperlipidaemic adults: a randomised controlled trial.
Jenkins D, Wong J, Kendall C, Esfahani A, Ng V, Leong T, Faulkner D, Vidgen E, Paul G, Mukherjea R, Krul E, Singer W
BMJ Open
Year of publication:
Page numbers:
Study Design:
Randomized Controlled Trial
Risk of Bias Assessment Rating:
Some concerns
Inclusion Criteria:
Healthy men and postmenopausal women between the ages of 21 and 70 years; high-normal or raised LDL-c concentrations (>131 mg/dl, 27 kg/m2; not currently involved in weight loss program.
Exclusion Criteria:
Lipid-lowering medications, hormone therapy, alcohol consumption >2 drinks/day, tobacco use, major CV event or surgery in preceding 6 months, diabetes, untreated hypothyroidism, blood pressure higher than 140/90 mmHg, renal or liver disease, cancer, or any food allergies
Research Purpose:
The main objective was to determine the longer term effect of a diet that was both low-carbohydrate and plant-based on weight loss and low-density lipoprotein cholesterol (LDL-C).
Blinding efforts:
Not applicable
Study Location:
Toronto, Ontario, Canada
Source(s) of Funding:
Government, Industry
Please specify names of funders:
Solae LLC, Loblaw Companies Limited, and the Canadian Research Chair Program of the Federal Government of Canada