VN: Nutrition Status Outcomes (2023)
Author and Year:
Barebring L, Lamberg-Allardt C, et al. 2023
PubMed ID:
Article Title:
Intake of Vitamin B12 inRrelation to Vitamin B12 Status in Groups Susceptible to Deficiency: a Systematic Review.
Authors:
Bärebring L, Lamberg-Allardt C, Thorisdottir B, Ramel A, Söderlund F, Arnesen E, Nwaru B, Dierkes J, Åkesson A
Journal:
Food & Nutrition Research
Year of publication:
2023
Volume:
67
Issue:
Page numbers:
Study Design:
Meta-analysis or Systematic Review
Risk of Bias Assessment Rating:
High
Inclusion Criteria:
The PI/ECOTSS included six healthy populations relevant for the Nordic setting: (1) children (0-18 years), (2) pregnant women, (3) lactating women, (4) young adults (18-35 years), (5) older adults (?65 years) and (6) vegetarians, including vegans; intervention/exposure included supplemental and dietary intake of vitamin B12; comparator was different levels of intake (including placebo); outcomes were defined as biological markers of vitamin B12 status, either B12, holoTC, MMA, tHcy in plasma or serum, or B12 in breastmilk; RCTs, cohort studies or case-control studies; cross-sectional studies for pregnant and lactating populations, due to the limited time frame of gestation and lactation; minimum study duration was 4 weeks for RCTs and 12m for prospective studies; observational studies were limited to European and North American populations.
Exclusion Criteria:
Not reported
Research Purpose:
The aim of this systematic review was to summarize the evidence for whether habitual or different levels of experimental intake of vitamin B12 from diet and supplements are sufficient to ensure adequate B12 status in children, pregnant and lactating women, young adults, older adults, vegetarians and vegans.
Blinding efforts:
Study Location:
Source(s) of Funding:
Government
Please specify names of funders:
Nordic Council of
Ministers and governmental food and health authorities
of Norway, Finland, Sweden, Denmark and Iceland