CRDA: Inflammatory Marker Outcomes (2023)

Intervention
In adults with overweight or obesity and no other established disease, what is the effect of carbohydrate (CHO) restriction compared to higher CHO diets on C-reactive protein?
- Conclusion
  Intake of a low- or moderate-carbohydrate (CHO) diet compared to a higher CHO intake may have no effect on C-reactive protein in adults with overweight or obesity and no other established disease; however the evidence is uncertain.
- Grade: Very Low (D)
  - Grade I means there is Good/Strong evidence supporting the statement;
  - Grade II is Fair;
  - Grade III is Limited/Weak;
  - Grade IV is Expert Opinion Only;
  - Grade V is Not Assignable.
  - High (A) means we are very confident that the true effect lies close to that of the estimate of the effect;
  - Moderate (B) means we are moderately confident in the effect estimate;
  - Low (C) means our confidence in the effect estimate is limited;
  - Very Low (D) means we have very little confidence in the effect estimate.
  - Ungraded means a grade is not assignable.
- Evidence Summary: In adults with overweight or obesity and no other established disease, what is the effect of carbohydrate (CHO) restriction compared to higher CHO diets on C-reactive protein?
- Search Plan and Results: CRDA: Overweight or Obesity and No Other Established Disease 2023