MiOA: Intervention: Community: Oral Nutrition Supplements (2023)

Author and Year:
Bauer J, Verlaan S, et al, 2015
PubMed ID:
Article Title:
Effects of a vitamin D and leucine-enriched whey protein nutritional supplement on measures of sarcopenia in older adults, the PROVIDE study: a randomized, double-blind, placebo-controlled trial.
Authors:
Bauer J, Verlaan S, Bautmans I, Brandt K, Donini L, Maggio M, McMurdo M, Mets T, Seal C, Wijers S, Ceda G, De Vito G, Donders G, Drey M, Greig C, Holmb├Ąck U, Narici M, McPhee J, Poggiogalle E, Power D, Scafoglieri A, Schultz R, Sieber C, Cederholm T
Journal:
Journal of the American Medical Directors Association
Year of publication:
2015
Volume:
16
Issue:
9
Page numbers:
740-7
Study Design:
Randomized Controlled Trial
Risk of Bias Assessment Rating:
Some concerns
Inclusion Criteria:
>/=65 years; mild to moderate limitations in physical function (SPPB score 4-9); low skeletal muscle mass index [SMI; (skeletal muscle mass/BW * 100) /=25); able and willing to provide informed consent.
Exclusion Criteria:
Comorbidities such as kidney or liver failure; malignancies over the past 5 years; anemia; acute inflammation (C-reactive protein concentration >10 mg/L); contraindications for calcium/vitamin D supplementation; using medication interfering with the nutritional intervention.
Research Purpose:
To test the hypothesis that a specific oral nutritional supplement can result in improvements in measures of sarcopenia.
Blinding efforts:
Double blind
Study Location:
Belgium, Germany, Ireland, Italy, Sweden, and the United Kingdom
Source(s) of Funding:
Industry
Please specify names of funders:
Nutricia Research, Nutricia Advanced Medical Nutrition